node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cds2 | Dgkg | ENSMUSP00000099470 | ENSMUSP00000087371 | Phosphatidate cytidylyltransferase 2; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin; Belongs to the CDS family. | Diacylglycerol kinase gamma. | 0.724 |
Cds2 | Mboat1 | ENSMUSP00000099470 | ENSMUSP00000045441 | Phosphatidate cytidylyltransferase 2; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin; Belongs to the CDS family. | Lysophospholipid acyltransferase 1; Acyltransferase which mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3- phosphoethanolamine or PE) (LPEAT activity). Catalyzes also the acylation of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3- phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn- glycero-3-phospho-L-serine or PS) (LPSAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phosph [...] | 0.902 |
Cds2 | Mboat2 | ENSMUSP00000099470 | ENSMUSP00000106567 | Phosphatidate cytidylyltransferase 2; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin; Belongs to the CDS family. | Lysophospholipid acyltransferase 2; Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity). To a lesser extent, also catalyzes the acylation of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3- phosphoethanolamine or PE) (LPEAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the [...] | 0.932 |
Cds2 | Pld1 | ENSMUSP00000099470 | ENSMUSP00000113810 | Phosphatidate cytidylyltransferase 2; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin; Belongs to the CDS family. | Phospholipase D1; Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic. | 0.928 |
Cds2 | Pld2 | ENSMUSP00000099470 | ENSMUSP00000104197 | Phosphatidate cytidylyltransferase 2; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin; Belongs to the CDS family. | Phospholipase D2; May have a role in signal-induced cytoskeletal regulation and/or endocytosis. | 0.922 |
Dgkg | Cds2 | ENSMUSP00000087371 | ENSMUSP00000099470 | Diacylglycerol kinase gamma. | Phosphatidate cytidylyltransferase 2; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin; Belongs to the CDS family. | 0.724 |
Dgkg | Gnpat | ENSMUSP00000087371 | ENSMUSP00000034466 | Diacylglycerol kinase gamma. | Dihydroxyacetone phosphate acyltransferase; Belongs to the GPAT/DAPAT family. | 0.834 |
Dgkg | Gpd2 | ENSMUSP00000087371 | ENSMUSP00000130992 | Diacylglycerol kinase gamma. | Glycerol-3-phosphate dehydrogenase, mitochondrial. | 0.815 |
Dgkg | Lpl | ENSMUSP00000087371 | ENSMUSP00000015712 | Diacylglycerol kinase gamma. | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. Belongs to the AB hydrolase superfamily. Lipase family. | 0.900 |
Dgkg | Mboat1 | ENSMUSP00000087371 | ENSMUSP00000045441 | Diacylglycerol kinase gamma. | Lysophospholipid acyltransferase 1; Acyltransferase which mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3- phosphoethanolamine or PE) (LPEAT activity). Catalyzes also the acylation of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3- phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn- glycero-3-phospho-L-serine or PS) (LPSAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phosph [...] | 0.732 |
Dgkg | Mboat2 | ENSMUSP00000087371 | ENSMUSP00000106567 | Diacylglycerol kinase gamma. | Lysophospholipid acyltransferase 2; Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity). To a lesser extent, also catalyzes the acylation of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3- phosphoethanolamine or PE) (LPEAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the [...] | 0.725 |
Dgkg | Plcb1 | ENSMUSP00000087371 | ENSMUSP00000105743 | Diacylglycerol kinase gamma. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.721 |
Dgkg | Plcb4 | ENSMUSP00000087371 | ENSMUSP00000105736 | Diacylglycerol kinase gamma. | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. | 0.728 |
Dgkg | Pld1 | ENSMUSP00000087371 | ENSMUSP00000113810 | Diacylglycerol kinase gamma. | Phospholipase D1; Implicated as a critical step in numerous cellular pathways, including signal transduction, membrane trafficking, and the regulation of mitosis. May be involved in the regulation of perinuclear intravesicular membrane traffic. | 0.747 |
Dgkg | Pld2 | ENSMUSP00000087371 | ENSMUSP00000104197 | Diacylglycerol kinase gamma. | Phospholipase D2; May have a role in signal-induced cytoskeletal regulation and/or endocytosis. | 0.752 |
Gnpat | Dgkg | ENSMUSP00000034466 | ENSMUSP00000087371 | Dihydroxyacetone phosphate acyltransferase; Belongs to the GPAT/DAPAT family. | Diacylglycerol kinase gamma. | 0.834 |
Gnpat | Gpd2 | ENSMUSP00000034466 | ENSMUSP00000130992 | Dihydroxyacetone phosphate acyltransferase; Belongs to the GPAT/DAPAT family. | Glycerol-3-phosphate dehydrogenase, mitochondrial. | 0.929 |
Gnpat | Mboat1 | ENSMUSP00000034466 | ENSMUSP00000045441 | Dihydroxyacetone phosphate acyltransferase; Belongs to the GPAT/DAPAT family. | Lysophospholipid acyltransferase 1; Acyltransferase which mediates the conversion of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3- phosphoethanolamine or PE) (LPEAT activity). Catalyzes also the acylation of lysophosphatidylserine (1-acyl-2-hydroxy-sn-glycero-3- phospho-L-serine or LPS) into phosphatidylserine (1,2-diacyl-sn- glycero-3-phospho-L-serine or PS) (LPSAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the phosph [...] | 0.801 |
Gnpat | Mboat2 | ENSMUSP00000034466 | ENSMUSP00000106567 | Dihydroxyacetone phosphate acyltransferase; Belongs to the GPAT/DAPAT family. | Lysophospholipid acyltransferase 2; Acyltransferase which mediates the conversion of lysophosphatidylcholine (1-acyl-sn-glycero-3-phosphocholine or LPC) into phosphatidylcholine (1,2-diacyl-sn-glycero-3-phosphocholine or PC) (LPCAT activity). To a lesser extent, also catalyzes the acylation of lysophosphatidylethanolamine (1-acyl-sn-glycero-3-phosphoethanolamine or LPE) into phosphatidylethanolamine (1,2-diacyl-sn-glycero-3- phosphoethanolamine or PE) (LPEAT activity). Prefers oleoyl-CoA as the acyl donor. Lysophospholipid acyltransferases (LPLATs) catalyze the reacylation step of the [...] | 0.812 |
Gpd2 | Dgkg | ENSMUSP00000130992 | ENSMUSP00000087371 | Glycerol-3-phosphate dehydrogenase, mitochondrial. | Diacylglycerol kinase gamma. | 0.815 |