node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gosr2 | Lman1l | ENSMUSP00000021329 | ENSMUSP00000091352 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Protein ERGIC-53-like. | 0.598 |
Gosr2 | Lman2l | ENSMUSP00000021329 | ENSMUSP00000110663 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity). | 0.585 |
Gosr2 | Mcfd2 | ENSMUSP00000021329 | ENSMUSP00000024963 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Multiple coagulation factor deficiency protein 2 homolog; The MCFD2-LMAN1 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. | 0.544 |
Gosr2 | Preb | ENSMUSP00000021329 | ENSMUSP00000074387 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Prolactin regulatory element-binding protein; Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER. | 0.750 |
Gosr2 | Sec22a | ENSMUSP00000021329 | ENSMUSP00000039568 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Vesicle-trafficking protein SEC22a; May be involved in vesicle transport between the ER and the Golgi complex; Belongs to the synaptobrevin family. | 0.935 |
Gosr2 | Sec22b | ENSMUSP00000021329 | ENSMUSP00000029476 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Vesicle-trafficking protein SEC22b; SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER; Belongs to the synaptobrevin family. | 0.999 |
Gosr2 | Sec22c | ENSMUSP00000021329 | ENSMUSP00000077628 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Vesicle-trafficking protein SEC22c; May be involved in vesicle transport between the ER and the Golgi complex; Belongs to the synaptobrevin family. | 0.928 |
Gosr2 | Sec23a | ENSMUSP00000021329 | ENSMUSP00000021375 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (By similarity). Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane ; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.765 |
Gosr2 | Tmed10 | ENSMUSP00000021329 | ENSMUSP00000037583 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Transmembrane emp24 domain-containing protein 10; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft [...] | 0.590 |
Gosr2 | Tmed2 | ENSMUSP00000021329 | ENSMUSP00000054834 | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | Transmembrane emp24 domain-containing protein 2; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle- mediated anterograde transport involved in the transport of GPI- anchored proteins and proposed to act together with TMED10 as their cargo receptor; the function specifically implies SEC24C and SEC24D of th [...] | 0.605 |
Lman1l | Gosr2 | ENSMUSP00000091352 | ENSMUSP00000021329 | Protein ERGIC-53-like. | Golgi SNAP receptor complex member 2; Involved in transport of proteins from the cis/medial-Golgi to the trans-Golgi network. | 0.598 |
Lman1l | Lman2l | ENSMUSP00000091352 | ENSMUSP00000110663 | Protein ERGIC-53-like. | VIP36-like protein; May be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. May function as a regulator of ERGIC-53 (By similarity). | 0.584 |
Lman1l | Mcfd2 | ENSMUSP00000091352 | ENSMUSP00000024963 | Protein ERGIC-53-like. | Multiple coagulation factor deficiency protein 2 homolog; The MCFD2-LMAN1 complex forms a specific cargo receptor for the ER-to-Golgi transport of selected proteins. | 0.927 |
Lman1l | Preb | ENSMUSP00000091352 | ENSMUSP00000074387 | Protein ERGIC-53-like. | Prolactin regulatory element-binding protein; Guanine nucleotide exchange factor that specifically activates the small GTPase SAR1B. Mediates the recruitment of SAR1B and other COPII coat components to endoplasmic reticulum membranes and is therefore required for the formation of COPII transport vesicles from the ER. | 0.590 |
Lman1l | Sec22a | ENSMUSP00000091352 | ENSMUSP00000039568 | Protein ERGIC-53-like. | Vesicle-trafficking protein SEC22a; May be involved in vesicle transport between the ER and the Golgi complex; Belongs to the synaptobrevin family. | 0.583 |
Lman1l | Sec22b | ENSMUSP00000091352 | ENSMUSP00000029476 | Protein ERGIC-53-like. | Vesicle-trafficking protein SEC22b; SNARE involved in targeting and fusion of ER-derived transport vesicles with the Golgi complex as well as Golgi-derived retrograde transport vesicles with the ER; Belongs to the synaptobrevin family. | 0.583 |
Lman1l | Sec22c | ENSMUSP00000091352 | ENSMUSP00000077628 | Protein ERGIC-53-like. | Vesicle-trafficking protein SEC22c; May be involved in vesicle transport between the ER and the Golgi complex; Belongs to the synaptobrevin family. | 0.583 |
Lman1l | Sec23a | ENSMUSP00000091352 | ENSMUSP00000021375 | Protein ERGIC-53-like. | Protein transport protein Sec23A; Component of the coat protein complex II (COPII) which promotes the formation of transport vesicles from the endoplasmic reticulum (ER). The coat has two main functions, the physical deformation of the endoplasmic reticulum membrane into vesicles and the selection of cargo molecules for their transport to the Golgi complex (By similarity). Required for the translocation of insulin-induced glucose transporter SLC2A4/GLUT4 to the cell membrane ; Belongs to the SEC23/SEC24 family. SEC23 subfamily. | 0.627 |
Lman1l | Tmed10 | ENSMUSP00000091352 | ENSMUSP00000037583 | Protein ERGIC-53-like. | Transmembrane emp24 domain-containing protein 10; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle-mediated anterograde transport involved in the transport of GPI-anchored proteins and proposed to act together with TMED2 as their cargo receptor; the function specifically implies SEC24C and SEC24D of the COPII vesicle coat and lipid raft [...] | 0.611 |
Lman1l | Tmed2 | ENSMUSP00000091352 | ENSMUSP00000054834 | Protein ERGIC-53-like. | Transmembrane emp24 domain-containing protein 2; Involved in vesicular protein trafficking. Mainly functions in the early secretory pathway but also in post-Golgi membranes. Thought to act as cargo receptor at the lumenal side for incorporation of secretory cargo molecules into transport vesicles and to be involved in vesicle coat formation at the cytoplasmic side. In COPII vesicle- mediated anterograde transport involved in the transport of GPI- anchored proteins and proposed to act together with TMED10 as their cargo receptor; the function specifically implies SEC24C and SEC24D of th [...] | 0.684 |