node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
9930104L06Rik | Fbxo47 | ENSMUSP00000154851 | ENSMUSP00000091471 | Uncharacterized protein C1orf109 homolog. | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | 0.584 |
Ccnf | Fbxo43 | ENSMUSP00000111048 | ENSMUSP00000054125 | Cyclin-F; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication. | F-box only protein 43; Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | 0.619 |
Ccnf | Fbxo47 | ENSMUSP00000111048 | ENSMUSP00000091471 | Cyclin-F; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication. | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | 0.548 |
Ect2l | Fbxo47 | ENSMUSP00000093497 | ENSMUSP00000091471 | Epithelial cell-transforming sequence 2 oncogene-like. | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | 0.570 |
Ect2l | Fbxo48 | ENSMUSP00000093497 | ENSMUSP00000057901 | Epithelial cell-transforming sequence 2 oncogene-like. | F-box only protein 48. | 0.644 |
Fbxo42 | Fbxo47 | ENSMUSP00000030757 | ENSMUSP00000091471 | F-box only protein 42; Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation (By similarity). | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | 0.606 |
Fbxo43 | Ccnf | ENSMUSP00000054125 | ENSMUSP00000111048 | F-box only protein 43; Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | Cyclin-F; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication. | 0.619 |
Fbxo43 | Fbxo47 | ENSMUSP00000054125 | ENSMUSP00000091471 | F-box only protein 43; Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | 0.649 |
Fbxo47 | 9930104L06Rik | ENSMUSP00000091471 | ENSMUSP00000154851 | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | Uncharacterized protein C1orf109 homolog. | 0.584 |
Fbxo47 | Ccnf | ENSMUSP00000091471 | ENSMUSP00000111048 | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | Cyclin-F; Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication. | 0.548 |
Fbxo47 | Ect2l | ENSMUSP00000091471 | ENSMUSP00000093497 | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | Epithelial cell-transforming sequence 2 oncogene-like. | 0.570 |
Fbxo47 | Fbxo42 | ENSMUSP00000091471 | ENSMUSP00000030757 | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | F-box only protein 42; Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation (By similarity). | 0.606 |
Fbxo47 | Fbxo43 | ENSMUSP00000091471 | ENSMUSP00000054125 | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | F-box only protein 43; Required to establish and maintain the arrest of oocytes at the second meiotic metaphase until fertilization. Probably acts by inhibiting the anaphase-promoting complex/cyclosome (APC/C) ubiquitin ligase. Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | 0.649 |
Fbxo47 | Fbxo48 | ENSMUSP00000091471 | ENSMUSP00000057901 | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | F-box only protein 48. | 0.701 |
Fbxo47 | M1ap | ENSMUSP00000091471 | ENSMUSP00000109613 | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | Meiosis 1 arrest protein; Required for meiosis I progression during spermatogenesis. | 0.656 |
Fbxo47 | Meig1 | ENSMUSP00000091471 | ENSMUSP00000070310 | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | Meiosis-expressed gene 1 protein; Essential for spermiogenesis; Belongs to the MEIG1 family. | 0.548 |
Fbxo47 | Spo11 | ENSMUSP00000091471 | ENSMUSP00000059056 | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | Meiotic recombination protein SPO11; [Isoform 1]: Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks (DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2. | 0.646 |
Fbxo47 | Terf1 | ENSMUSP00000091471 | ENSMUSP00000140744 | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | Telomeric repeat-binding factor 1; Binds the telomeric double-stranded 5'-TTAGGG-3' repeat and negatively regulates telomere length. Involved in the regulation of the mitotic spindle. Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded 5'-TTAGGG-3' repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. | 0.672 |
Fbxo48 | Ect2l | ENSMUSP00000057901 | ENSMUSP00000093497 | F-box only protein 48. | Epithelial cell-transforming sequence 2 oncogene-like. | 0.644 |
Fbxo48 | Fbxo47 | ENSMUSP00000057901 | ENSMUSP00000091471 | F-box only protein 48. | F-box only protein 47; Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. | 0.701 |