Car1 protein (mouse) - STRING interaction network

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Score

Car1

Carbonic anhydrase 1; Reversible hydration of carbon dioxide. (261 aa)

Predicted Functional Partners:

Car2

0.818

Alb

0.644

Slc4a1

0.643

Epb42

0.629

Padi2

0.584

Rpf2

0.568

Prdx2

0.564

Car3

0.544

Alas2

0.544

Car7

0.543

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Alas2	Car1	ENSMUSP00000066040	ENSMUSP00000137926	5-aminolevulinate synthase, erythroid-specific, mitochondrial.	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	0.544
Alas2	Epb42	ENSMUSP00000066040	ENSMUSP00000099548	5-aminolevulinate synthase, erythroid-specific, mitochondrial.	Erythrocyte membrane protein band 4.2; Probably plays an important role in the regulation of erythrocyte shape and mechanical properties; Belongs to the transglutaminase superfamily. Transglutaminase family.	0.831
Alas2	Slc4a1	ENSMUSP00000066040	ENSMUSP00000006749	5-aminolevulinate synthase, erythroid-specific, mitochondrial.	Band 3 anion transport protein; Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride- bicarbonate exch [...]	0.884
Alb	Car1	ENSMUSP00000031314	ENSMUSP00000137926	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	0.644
Alb	Car2	ENSMUSP00000031314	ENSMUSP00000029078	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton- coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6; Belongs to the alpha-carbonic anhydrase family.	0.428
Alb	Car3	ENSMUSP00000031314	ENSMUSP00000029076	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Carbonic anhydrase 3; Reversible hydration of carbon dioxide.	0.594
Alb	Car7	ENSMUSP00000031314	ENSMUSP00000052136	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Carbonic anhydrase 7; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family.	0.513
Alb	Prdx2	ENSMUSP00000031314	ENSMUSP00000105356	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	Peroxiredoxin-2; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).	0.491
Car1	Alas2	ENSMUSP00000137926	ENSMUSP00000066040	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	5-aminolevulinate synthase, erythroid-specific, mitochondrial.	0.544
Car1	Alb	ENSMUSP00000137926	ENSMUSP00000031314	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.644
Car1	Car2	ENSMUSP00000137926	ENSMUSP00000029078	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton- coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6; Belongs to the alpha-carbonic anhydrase family.	0.818
Car1	Car3	ENSMUSP00000137926	ENSMUSP00000029076	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	Carbonic anhydrase 3; Reversible hydration of carbon dioxide.	0.544
Car1	Car7	ENSMUSP00000137926	ENSMUSP00000052136	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	Carbonic anhydrase 7; Reversible hydration of carbon dioxide; Belongs to the alpha-carbonic anhydrase family.	0.543
Car1	Epb42	ENSMUSP00000137926	ENSMUSP00000099548	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	Erythrocyte membrane protein band 4.2; Probably plays an important role in the regulation of erythrocyte shape and mechanical properties; Belongs to the transglutaminase superfamily. Transglutaminase family.	0.629
Car1	Padi2	ENSMUSP00000137926	ENSMUSP00000030765	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	Protein-arginine deiminase type-2; Catalyzes the deimination of arginine residues of proteins.	0.584
Car1	Prdx2	ENSMUSP00000137926	ENSMUSP00000105356	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	Peroxiredoxin-2; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides and as sensor of hydrogen peroxide-mediated signaling events. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).	0.564
Car1	Rpf2	ENSMUSP00000137926	ENSMUSP00000138581	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	Ribosome production factor 2 homolog; Involved in ribosomal large subunit assembly. May regulate the localization of the 5S RNP/5S ribonucleoprotein particle to the nucleolus; Belongs to the RPF2 family.	0.568
Car1	Slc4a1	ENSMUSP00000137926	ENSMUSP00000006749	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	Band 3 anion transport protein; Functions both as a transporter that mediates electroneutral anion exchange across the cell membrane and as a structural protein. Major integral membrane glycoprotein of the erythrocyte membrane; required for normal flexibility and stability of the erythrocyte membrane and for normal erythrocyte shape via the interactions of its cytoplasmic domain with cytoskeletal proteins, glycolytic enzymes, and hemoglobin. Functions as a transporter that mediates the 1:1 exchange of inorganic anions across the erythrocyte membrane. Mediates chloride- bicarbonate exch [...]	0.643
Car2	Alb	ENSMUSP00000029078	ENSMUSP00000031314	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton- coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6; Belongs to the alpha-carbonic anhydrase family.	Serum albumin; Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc (By similarity). Major calcium and magnesium transporter in plasma, binds approximately 45% of circulating calcium and magnesium in plasma (By similarity). Potentially has more than two calcium-binding sites and might additionally bind calcium in a non-specific manner (B [...]	0.428
Car2	Car1	ENSMUSP00000029078	ENSMUSP00000137926	Carbonic anhydrase 2; Essential for bone resorption and osteoclast differentiation. Reversible hydration of carbon dioxide. Contributes to intracellular pH regulation in the duodenal upper villous epithelium during proton- coupled peptide absorption. Stimulates the chloride-bicarbonate exchange activity of SLC26A6; Belongs to the alpha-carbonic anhydrase family.	Carbonic anhydrase 1; Reversible hydration of carbon dioxide.	0.818