node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Anxa1 | App | ENSMUSP00000025561 | ENSMUSP00000005406 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing. Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contributes to the adapti [...] | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G [...] | 0.633 |
Anxa1 | Fpr-rs6 | ENSMUSP00000025561 | ENSMUSP00000093296 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing. Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contributes to the adapti [...] | Formyl peptide receptor-related sequence 6; May have an olfactory function associated with the identification of pathogens or of pathogenic states. | 0.614 |
Anxa1 | Fpr3 | ENSMUSP00000025561 | ENSMUSP00000093316 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing. Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contributes to the adapti [...] | Formyl peptide receptor-related sequence 1; Low affinity receptor for N-formyl-methionyl peptides. Receptor for lipoxin A4. May have an olfactory function associated with the identification of pathogens or of pathogenic states. | 0.998 |
Anxa1 | Hebp1 | ENSMUSP00000025561 | ENSMUSP00000042232 | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing. Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contributes to the adapti [...] | Heme-binding protein 1; May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities. | 0.528 |
App | Anxa1 | ENSMUSP00000005406 | ENSMUSP00000025561 | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G [...] | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing. Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contributes to the adapti [...] | 0.633 |
App | Fpr-rs6 | ENSMUSP00000005406 | ENSMUSP00000093296 | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G [...] | Formyl peptide receptor-related sequence 6; May have an olfactory function associated with the identification of pathogens or of pathogenic states. | 0.626 |
App | Fpr3 | ENSMUSP00000005406 | ENSMUSP00000093316 | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G [...] | Formyl peptide receptor-related sequence 1; Low affinity receptor for N-formyl-methionyl peptides. Receptor for lipoxin A4. May have an olfactory function associated with the identification of pathogens or of pathogenic states. | 0.868 |
App | Hebp1 | ENSMUSP00000005406 | ENSMUSP00000042232 | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G [...] | Heme-binding protein 1; May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities. | 0.503 |
Egr1 | Fpr-rs6 | ENSMUSP00000069616 | ENSMUSP00000093296 | Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'- GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Activates expression of p53/TP53 and TGFB1, and thereby helps prevent tumor form [...] | Formyl peptide receptor-related sequence 6; May have an olfactory function associated with the identification of pathogens or of pathogenic states. | 0.538 |
Egr1 | Vmn1r50 | ENSMUSP00000069616 | ENSMUSP00000154560 | Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'- GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Activates expression of p53/TP53 and TGFB1, and thereby helps prevent tumor form [...] | Vomeronasal type-1 receptor 50; Putative pheromone receptor implicated in the regulation of social and reproductive behavior; Belongs to the G-protein coupled receptor 1 family. | 0.542 |
Egr1 | Vmn2r120 | ENSMUSP00000069616 | ENSMUSP00000129296 | Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'- GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Activates expression of p53/TP53 and TGFB1, and thereby helps prevent tumor form [...] | Vomeronasal 2, receptor 120. | 0.546 |
Fpr-rs6 | Anxa1 | ENSMUSP00000093296 | ENSMUSP00000025561 | Formyl peptide receptor-related sequence 6; May have an olfactory function associated with the identification of pathogens or of pathogenic states. | Annexin A1; Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Promotes resolution of inflammation and wound healing. Functions at least in part by activating the formyl peptide receptors and downstream signaling cascades. Promotes chemotaxis of granulocytes and monocytes via activation of the formyl peptide receptors (By similarity). Contributes to the adapti [...] | 0.614 |
Fpr-rs6 | App | ENSMUSP00000093296 | ENSMUSP00000005406 | Formyl peptide receptor-related sequence 6; May have an olfactory function associated with the identification of pathogens or of pathogenic states. | Gamma-secretase C-terminal fragment 50; Functions as a cell surface receptor and performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Interaction between APP molecules on neighboring cells promotes synaptogenesis. Involved in cell mobility and transcription regulation through protein-protein interactions. Can promote transcription activation through binding to APBB1-KAT5 and inhibit Notch signaling through interaction with Numb. Couples to apoptosis-inducing pathways such as those mediated by G(O) and JIP. Inhibits G [...] | 0.626 |
Fpr-rs6 | Egr1 | ENSMUSP00000093296 | ENSMUSP00000069616 | Formyl peptide receptor-related sequence 6; May have an olfactory function associated with the identification of pathogens or of pathogenic states. | Early growth response protein 1; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'- GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status (By similarity). Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Activates expression of p53/TP53 and TGFB1, and thereby helps prevent tumor form [...] | 0.538 |
Fpr-rs6 | Fpr3 | ENSMUSP00000093296 | ENSMUSP00000093316 | Formyl peptide receptor-related sequence 6; May have an olfactory function associated with the identification of pathogens or of pathogenic states. | Formyl peptide receptor-related sequence 1; Low affinity receptor for N-formyl-methionyl peptides. Receptor for lipoxin A4. May have an olfactory function associated with the identification of pathogens or of pathogenic states. | 0.601 |
Fpr-rs6 | Hebp1 | ENSMUSP00000093296 | ENSMUSP00000042232 | Formyl peptide receptor-related sequence 6; May have an olfactory function associated with the identification of pathogens or of pathogenic states. | Heme-binding protein 1; May bind free porphyrinogens that may be present in the cell and thus facilitate removal of these potentially toxic compound. Binds with a high affinity to one molecule of heme or porphyrins. It binds metalloporphyrins, free porphyrins and N-methylprotoporphyrin with similar affinities. | 0.738 |
Fpr-rs6 | Olfr1183 | ENSMUSP00000093296 | ENSMUSP00000151738 | Formyl peptide receptor-related sequence 6; May have an olfactory function associated with the identification of pathogens or of pathogenic states. | Olfactory receptor. | 0.595 |
Fpr-rs6 | Vmn1r50 | ENSMUSP00000093296 | ENSMUSP00000154560 | Formyl peptide receptor-related sequence 6; May have an olfactory function associated with the identification of pathogens or of pathogenic states. | Vomeronasal type-1 receptor 50; Putative pheromone receptor implicated in the regulation of social and reproductive behavior; Belongs to the G-protein coupled receptor 1 family. | 0.596 |
Fpr-rs6 | Vmn1r51 | ENSMUSP00000093296 | ENSMUSP00000153783 | Formyl peptide receptor-related sequence 6; May have an olfactory function associated with the identification of pathogens or of pathogenic states. | Vomeronasal type-1 receptor 51; Putative pheromone receptor implicated in the regulation of social as well as reproductive behavior; Belongs to the G-protein coupled receptor 1 family. | 0.576 |
Fpr-rs6 | Vmn1r80 | ENSMUSP00000093296 | ENSMUSP00000153967 | Formyl peptide receptor-related sequence 6; May have an olfactory function associated with the identification of pathogens or of pathogenic states. | Vomeronasal type-1 receptor. | 0.604 |