node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mrpl21 | Mrpl36 | ENSMUSP00000025745 | ENSMUSP00000022098 | 39S ribosomal protein L21, mitochondrial. | 39S ribosomal protein L36, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family. | 0.999 |
Mrpl21 | Mrps16 | ENSMUSP00000025745 | ENSMUSP00000055619 | 39S ribosomal protein L21, mitochondrial. | 28S ribosomal protein S16, mitochondrial; Belongs to the bacterial ribosomal protein bS16 family. | 0.999 |
Mrpl21 | Rpl23 | ENSMUSP00000025745 | ENSMUSP00000099435 | 39S ribosomal protein L21, mitochondrial. | 60S ribosomal protein L23. | 0.999 |
Mrpl21 | Rpl23a | ENSMUSP00000025745 | ENSMUSP00000099541 | 39S ribosomal protein L21, mitochondrial. | 60S ribosomal protein L23a; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA (By similarity). May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination (By similarity); Belongs to the universal ribosomal protein uL23 family. | 0.999 |
Mrpl21 | Rpl5 | ENSMUSP00000025745 | ENSMUSP00000080854 | 39S ribosomal protein L21, mitochondrial. | 60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.999 |
Mrpl21 | Rps11 | ENSMUSP00000025745 | ENSMUSP00000003521 | 39S ribosomal protein L21, mitochondrial. | 40S ribosomal protein S11. | 0.999 |
Mrpl21 | Rps15 | ENSMUSP00000025745 | ENSMUSP00000069004 | 39S ribosomal protein L21, mitochondrial. | 40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. | 0.999 |
Mrpl21 | Rps3 | ENSMUSP00000025745 | ENSMUSP00000032998 | 39S ribosomal protein L21, mitochondrial. | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit (By similarity). Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (By similarity). Displays high binding affinity for 7,8-dihydro-8- oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (By similarity). Has also been shown to bind with similar affinity to intact and damaged DNA (By similarity). S [...] | 0.999 |
Mrpl21 | Tsfm | ENSMUSP00000025745 | ENSMUSP00000042134 | 39S ribosomal protein L21, mitochondrial. | Elongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.973 |
Mrpl21 | Tufm | ENSMUSP00000025745 | ENSMUSP00000095656 | 39S ribosomal protein L21, mitochondrial. | Elongation factor Tu, mitochondrial; Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG- I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.999 |
Mrpl36 | Mrpl21 | ENSMUSP00000022098 | ENSMUSP00000025745 | 39S ribosomal protein L36, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family. | 39S ribosomal protein L21, mitochondrial. | 0.999 |
Mrpl36 | Mrps16 | ENSMUSP00000022098 | ENSMUSP00000055619 | 39S ribosomal protein L36, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family. | 28S ribosomal protein S16, mitochondrial; Belongs to the bacterial ribosomal protein bS16 family. | 0.999 |
Mrpl36 | Rpl23 | ENSMUSP00000022098 | ENSMUSP00000099435 | 39S ribosomal protein L36, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family. | 60S ribosomal protein L23. | 0.999 |
Mrpl36 | Rpl23a | ENSMUSP00000022098 | ENSMUSP00000099541 | 39S ribosomal protein L36, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family. | 60S ribosomal protein L23a; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA (By similarity). May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination (By similarity); Belongs to the universal ribosomal protein uL23 family. | 0.999 |
Mrpl36 | Rpl5 | ENSMUSP00000022098 | ENSMUSP00000080854 | 39S ribosomal protein L36, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family. | 60S ribosomal protein L5; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through [...] | 0.999 |
Mrpl36 | Rps11 | ENSMUSP00000022098 | ENSMUSP00000003521 | 39S ribosomal protein L36, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family. | 40S ribosomal protein S11. | 0.999 |
Mrpl36 | Rps15 | ENSMUSP00000022098 | ENSMUSP00000069004 | 39S ribosomal protein L36, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family. | 40S ribosomal protein S15; Belongs to the universal ribosomal protein uS19 family. | 0.999 |
Mrpl36 | Rps3 | ENSMUSP00000022098 | ENSMUSP00000032998 | 39S ribosomal protein L36, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family. | 40S ribosomal protein S3; Involved in translation as a component of the 40S small ribosomal subunit (By similarity). Has endonuclease activity and plays a role in repair of damaged DNA. Cleaves phosphodiester bonds of DNAs containing altered bases with broad specificity and cleaves supercoiled DNA more efficiently than relaxed DNA (By similarity). Displays high binding affinity for 7,8-dihydro-8- oxoguanine (8-oxoG), a common DNA lesion caused by reactive oxygen species (ROS) (By similarity). Has also been shown to bind with similar affinity to intact and damaged DNA (By similarity). S [...] | 0.999 |
Mrpl36 | Tsfm | ENSMUSP00000022098 | ENSMUSP00000042134 | 39S ribosomal protein L36, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family. | Elongation factor Ts, mitochondrial; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. | 0.806 |
Mrpl36 | Tufm | ENSMUSP00000022098 | ENSMUSP00000095656 | 39S ribosomal protein L36, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family. | Elongation factor Tu, mitochondrial; Promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis. Plays also a role in the regulation of autophagy and innate immunity. Recruits ATG5-ATG12 and NLRX1 at mitochondria and serves as a checkpoint of the RIG- I/DDX58-MAVS pathway. In turn, inhibits RLR-mediated type I interferon while promoting autophagy; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. | 0.999 |