Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Hemoglobin, beta adult minor chain; Involved in oxygen transport from the lung to the various peripheral tissues (147 aa)
Predicted Functional Partners:
Hemoglobin alpha, adult chain 1; Involved in oxygen transport from the lung to the various peripheral tissues (142 aa)
Hemoglobin alpha, adult chain 2 (142 aa)
Hemoglobin, beta adult major chain (147 aa)
Haptoglobin; As a result of hemolysis, hemoglobin is found to accumulate in the kidney and is secreted in the urine. Haptoglobin captures, and combines with free plasma hemoglobin to allow hepatic recycling of heme iron and to prevent kidney damage. Haptoglobin also acts as an antioxidant, has antibacterial activity and plays a role in modulating many aspects of the acute phase response. Hemoglobin/haptoglobin complexes are rapidely cleared by the macrophage CD163 scavenger receptor expressed on the surface of liver Kupfer cells through an endocytic lysosomal degradation pathway (By si [...] (347 aa)
Hemoglobin X, alpha-like embryonic chain in Hba complex; The zeta chain is an alpha-type chain of mammalian embryonic hemoglobin (142 aa)