STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
KrtdapKeratinocyte differentiation-associated protein; May act as a soluble regulator of keratinocyte differentiation. May play an important role in embryonic skin morphogenesis (By similarity). (102 aa)    
Predicted Functional Partners:
Sbsn
Suprabasin.
   
  
 0.918
Cnfn
Cornifelin; Part of the insoluble cornified cell envelope (CE) of stratified squamous epithelia.
   
  
 0.833
Dmkn
Dermokine; May act as a soluble regulator of keratinocyte differentiation.
   
  
 0.778
Calm4
Calmodulin-4; Implicated in the early stage of ectopic ossification.
   
  
 0.771
Lor
Loricrin; Major keratinocyte cell envelope protein.
   
  
 0.739
Krt5
Keratin, type II cytoskeletal 5.
   
  
 0.721
Krt4
Keratin, type II cytoskeletal 4.
   
  
 0.718
Krt13
Keratin, type I cytoskeletal 13.
   
  
 0.699
Sprr3
Small proline-rich protein 3; Cross-linked envelope protein of keratinocytes; Belongs to the cornifin (SPRR) family.
   
  
 0.687
Lgals7
Galectin-7; Could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. Pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release (By similarity).
   
  
 0.687
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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