node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cylc2 | Odf1 | ENSMUSP00000039750 | ENSMUSP00000080632 | Cylicin, basic protein of sperm head cytoskeleton 2. | Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. | 0.449 |
Cylc2 | Smcp | ENSMUSP00000039750 | ENSMUSP00000096487 | Cylicin, basic protein of sperm head cytoskeleton 2. | Sperm mitochondrial-associated cysteine-rich protein; Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida. | 0.601 |
Cylc2 | Spata6 | ENSMUSP00000039750 | ENSMUSP00000036964 | Cylicin, basic protein of sperm head cytoskeleton 2. | Spermatogenesis-associated protein 6; Required for formation of the sperm connecting piece during spermiogenesis. Sperm connecting piece is essential for linking the developing flagellum to the head during late spermiogenesis. May be involved in myosin-based microfilament transport through interaction with myosin subunits. | 0.569 |
Cylc2 | Spesp1 | ENSMUSP00000039750 | ENSMUSP00000058522 | Cylicin, basic protein of sperm head cytoskeleton 2. | Sperm equatorial segment protein 1; Involved in fertilization ability of sperm. | 0.514 |
Cylc2 | Zan | ENSMUSP00000039750 | ENSMUSP00000114068 | Cylicin, basic protein of sperm head cytoskeleton 2. | Zonadhesin; Binds in a species-specific manner to the zona pellucida of the egg. May be involved in gamete recognition and/or signaling. | 0.514 |
Fscb | Hils1 | ENSMUSP00000051554 | ENSMUSP00000039866 | Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium. | Spermatid-specific linker histone H1-like protein; DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa; Belongs to the histone H1/H5 family. | 0.688 |
Fscb | Smcp | ENSMUSP00000051554 | ENSMUSP00000096487 | Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium. | Sperm mitochondrial-associated cysteine-rich protein; Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida. | 0.620 |
Fscb | Tmem190 | ENSMUSP00000051554 | ENSMUSP00000013235 | Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium. | Transmembrane protein 190. | 0.800 |
Hils1 | Fscb | ENSMUSP00000039866 | ENSMUSP00000051554 | Spermatid-specific linker histone H1-like protein; DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa; Belongs to the histone H1/H5 family. | Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium. | 0.688 |
Hils1 | Odf1 | ENSMUSP00000039866 | ENSMUSP00000080632 | Spermatid-specific linker histone H1-like protein; DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa; Belongs to the histone H1/H5 family. | Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. | 0.520 |
Hils1 | Smcp | ENSMUSP00000039866 | ENSMUSP00000096487 | Spermatid-specific linker histone H1-like protein; DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa; Belongs to the histone H1/H5 family. | Sperm mitochondrial-associated cysteine-rich protein; Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida. | 0.501 |
Hils1 | Tmem190 | ENSMUSP00000039866 | ENSMUSP00000013235 | Spermatid-specific linker histone H1-like protein; DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa; Belongs to the histone H1/H5 family. | Transmembrane protein 190. | 0.737 |
Odf1 | Cylc2 | ENSMUSP00000080632 | ENSMUSP00000039750 | Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. | Cylicin, basic protein of sperm head cytoskeleton 2. | 0.449 |
Odf1 | Hils1 | ENSMUSP00000080632 | ENSMUSP00000039866 | Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. | Spermatid-specific linker histone H1-like protein; DNA-binding protein that may be implicated in chromatin remodeling and/or transcriptional regulation during spermiogenesis, the process of spermatid maturation into spermatozoa; Belongs to the histone H1/H5 family. | 0.520 |
Odf1 | Smcp | ENSMUSP00000080632 | ENSMUSP00000096487 | Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. | Sperm mitochondrial-associated cysteine-rich protein; Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida. | 0.713 |
Odf1 | Spata21 | ENSMUSP00000080632 | ENSMUSP00000053080 | Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. | Spermatogenesis-associated protein 21; Involved in the differentiation of haploid spermatids. | 0.472 |
Odf1 | Spata6 | ENSMUSP00000080632 | ENSMUSP00000036964 | Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. | Spermatogenesis-associated protein 6; Required for formation of the sperm connecting piece during spermiogenesis. Sperm connecting piece is essential for linking the developing flagellum to the head during late spermiogenesis. May be involved in myosin-based microfilament transport through interaction with myosin subunits. | 0.756 |
Odf1 | Spesp1 | ENSMUSP00000080632 | ENSMUSP00000058522 | Outer dense fiber protein 1; Component of the outer dense fibers (ODF) of spermatozoa. ODF are filamentous structures located on the outside of the axoneme in the midpiece and principal piece of the mammalian sperm tail and may help to maintain the passive elastic structures and elastic recoil of the sperm tail. | Sperm equatorial segment protein 1; Involved in fertilization ability of sperm. | 0.642 |
Smcp | Cylc2 | ENSMUSP00000096487 | ENSMUSP00000039750 | Sperm mitochondrial-associated cysteine-rich protein; Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida. | Cylicin, basic protein of sperm head cytoskeleton 2. | 0.601 |
Smcp | Fscb | ENSMUSP00000096487 | ENSMUSP00000051554 | Sperm mitochondrial-associated cysteine-rich protein; Involved in sperm motility. Its absence is associated with genetic background dependent male infertility. Infertility may be due to reduced sperm motility in the female reproductive tract and inability to penetrate the oocyte zona pellucida. | Fibrous sheath CABYR-binding protein; May be involved in the later stages of fibrous sheath biogenesis and spermatozoa capacitation. Inhibits ROPN1 and ROPN1L SUMOylation. Binds calcium. | 0.620 |