STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Defb25Beta-defensin 25; Has antibacterial activity; Belongs to the beta-defensin family. (71 aa)    
Predicted Functional Partners:
Defb48
Predicted gene, EG432867.
   
 
 0.822
Defb18
Beta-defensin 18; Has antibacterial activity; Belongs to the beta-defensin family.
   
 
 0.812
Defb47
Predicted gene, EG654465.
   
 
 0.806
Defb36
Beta-defensin 36; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.771
Defb30
Beta-defensin 30; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.765
Defb42
Beta-defensin 42; Has bactericidal activity (By similarity). May play a role in the antimicrobial protection of sperm and urogenital tract epithelia ; Belongs to the beta-defensin family.
     
 0.752
Defb45
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.741
Defb19
Beta-defensin 19; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.703
Defb28
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
     
 0.680
Defb21
Beta-defensin; Has antibacterial activity; Belongs to the beta-defensin family.
   
 
 0.669
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.