Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ankef1 | Lgals12 | ENSMUSP00000113881 | ENSMUSP00000097318 | Ankyrin repeat and EF-hand domain-containing protein 1. | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | 0.535 |
| Ankef1 | Mindy3 | ENSMUSP00000113881 | ENSMUSP00000028105 | Ankyrin repeat and EF-hand domain-containing protein 1. | Ubiquitin carboxyl-terminal hydrolase MINDY-3; Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins. | 0.703 |
| Calcoco2 | Lgals12 | ENSMUSP00000087407 | ENSMUSP00000097318 | Calcium-binding and coiled-coil domain-containing protein 2; Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation (By similarity). Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy (By similarity). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen- containing autophagosome maturation (By similarity). Bacteria targeting [...] | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | 0.637 |
| Lep | Lgals12 | ENSMUSP00000067046 | ENSMUSP00000097318 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal met [...] | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | 0.438 |
| Lep | Retn | ENSMUSP00000067046 | ENSMUSP00000133024 | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal met [...] | Resistin; Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes; Belongs to the resistin/FIZZ family. | 0.939 |
| Lgals12 | Ankef1 | ENSMUSP00000097318 | ENSMUSP00000113881 | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | Ankyrin repeat and EF-hand domain-containing protein 1. | 0.535 |
| Lgals12 | Calcoco2 | ENSMUSP00000097318 | ENSMUSP00000087407 | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | Calcium-binding and coiled-coil domain-containing protein 2; Xenophagy-specific receptor required for autophagy-mediated intracellular bacteria degradation (By similarity). Acts as an effector protein of galectin-sensed membrane damage that restricts the proliferation of infecting pathogens upon entry into the cytosol by targeting LGALS8-associated bacteria for autophagy (By similarity). Initially orchestrates bacteria targeting to autophagosomes and subsequently ensures pathogen degradation by regulating pathogen- containing autophagosome maturation (By similarity). Bacteria targeting [...] | 0.637 |
| Lgals12 | Lep | ENSMUSP00000097318 | ENSMUSP00000067046 | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal met [...] | 0.438 |
| Lgals12 | Lgals2 | ENSMUSP00000097318 | ENSMUSP00000036598 | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | Galectin-2; This protein binds beta-galactoside. Its physiological function is not yet known. | 0.555 |
| Lgals12 | Mindy3 | ENSMUSP00000097318 | ENSMUSP00000028105 | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | Ubiquitin carboxyl-terminal hydrolase MINDY-3; Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins. | 0.490 |
| Lgals12 | Retn | ENSMUSP00000097318 | ENSMUSP00000133024 | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | Resistin; Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes; Belongs to the resistin/FIZZ family. | 0.520 |
| Lgals12 | Timp4 | ENSMUSP00000097318 | ENSMUSP00000032462 | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | Metalloproteinase inhibitor 4; Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. | 0.477 |
| Lgals12 | Vps13a | ENSMUSP00000097318 | ENSMUSP00000068716 | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | Vacuolar protein sorting-associated protein 13A; May play a role in the control of protein cycling through the trans-Golgi network to early and late endosomes, lysosomes and plasma membrane. | 0.456 |
| Lgals12 | Vps13c | ENSMUSP00000097318 | ENSMUSP00000077040 | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | Vacuolar protein sorting-associated protein 13C; Necessary for proper mitochondrial function and maintenance of mitochondrial transmembrane potential. Involved in the regulation of PINK1/PRKN-mediated mitophagy in response to mitochondrial depolarization. | 0.526 |
| Lgals12 | Vstm4 | ENSMUSP00000097318 | ENSMUSP00000055178 | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | V-set and transmembrane domain-containing protein 4; Peptide Lv enhances L-type voltage-gated calcium channel (L- VGCC) currents in retinal photoreceptors. | 0.525 |
| Lgals2 | Lgals12 | ENSMUSP00000036598 | ENSMUSP00000097318 | Galectin-2; This protein binds beta-galactoside. Its physiological function is not yet known. | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | 0.555 |
| Mindy3 | Ankef1 | ENSMUSP00000028105 | ENSMUSP00000113881 | Ubiquitin carboxyl-terminal hydrolase MINDY-3; Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins. | Ankyrin repeat and EF-hand domain-containing protein 1. | 0.703 |
| Mindy3 | Lgals12 | ENSMUSP00000028105 | ENSMUSP00000097318 | Ubiquitin carboxyl-terminal hydrolase MINDY-3; Hydrolase that can remove 'Lys-48'-linked conjugated ubiquitin from proteins. | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | 0.490 |
| Retn | Lep | ENSMUSP00000133024 | ENSMUSP00000067046 | Resistin; Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes; Belongs to the resistin/FIZZ family. | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo-pituitary-adrenal hormones. In the periphery, increases basal met [...] | 0.939 |
| Retn | Lgals12 | ENSMUSP00000133024 | ENSMUSP00000097318 | Resistin; Hormone that seems to suppress insulin ability to stimulate glucose uptake into adipose cells. Potentially links obesity to diabetes; Belongs to the resistin/FIZZ family. | Galectin-12; Binds lactose. May participate in the apoptosis of adipocytes. | 0.520 |
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