Smim10l1 protein (mouse) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Gm49948	Smim10l1	ENSMUSP00000109426	ENSMUSP00000139452	Predicted gene, 49948.	Small integral membrane protein 10-like 1.	0.501
Igsf5	Smim10l1	ENSMUSP00000109425	ENSMUSP00000139452	Immunoglobulin superfamily member 5; Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells; Belongs to the immunoglobulin superfamily.	Small integral membrane protein 10-like 1.	0.471
Lacc1	Smim10l1	ENSMUSP00000059173	ENSMUSP00000139452	Laccase domain-containing protein 1; Central regulator of the metabolic function and bioenergetic state of macrophages. In macrophages, promotes flux through de novo lipogenesis to concomitantly drive high levels of both fatty-acid oxidation and glycolysis.	Small integral membrane protein 10-like 1.	0.480
Smim10l1	Gm49948	ENSMUSP00000139452	ENSMUSP00000109426	Small integral membrane protein 10-like 1.	Predicted gene, 49948.	0.501
Smim10l1	Igsf5	ENSMUSP00000139452	ENSMUSP00000109425	Small integral membrane protein 10-like 1.	Immunoglobulin superfamily member 5; Provides, together with MAGI1, an adhesion machinery at tight junctions, which may regulate the permeability of kidney glomerulus and small intestinal epithelial cells. Mediates calcium-independent homophilic cell adhesion. In testis, it may function as a cell adhesion molecule rather than a tight-junction protein. It may participate in the adhesion between spermatogonia-spermatogonia, spermatogonia-Sertoli cells, and Sertoli cells-Sertoli cells; Belongs to the immunoglobulin superfamily.	0.471
Smim10l1	Lacc1	ENSMUSP00000139452	ENSMUSP00000059173	Small integral membrane protein 10-like 1.	Laccase domain-containing protein 1; Central regulator of the metabolic function and bioenergetic state of macrophages. In macrophages, promotes flux through de novo lipogenesis to concomitantly drive high levels of both fatty-acid oxidation and glycolysis.	0.480
Smim10l1	Tas2r131	ENSMUSP00000139452	ENSMUSP00000080736	Small integral membrane protein 10-like 1.	Taste receptor type 2.	0.615
Smim10l1	Tas2r143	ENSMUSP00000139452	ENSMUSP00000057910	Small integral membrane protein 10-like 1.	Taste receptor type 2 member 143; Putative taste receptor which may play a role in the perception of bitterness.	0.610
Smim10l1	Tmem254a	ENSMUSP00000139452	ENSMUSP00000098374	Small integral membrane protein 10-like 1.	Transmembrane protein 254a.	0.475
Smim10l1	Tmem254b	ENSMUSP00000139452	ENSMUSP00000098369	Small integral membrane protein 10-like 1.	Transmembrane protein 254.	0.415
Tas2r131	Smim10l1	ENSMUSP00000080736	ENSMUSP00000139452	Taste receptor type 2.	Small integral membrane protein 10-like 1.	0.615
Tas2r143	Smim10l1	ENSMUSP00000057910	ENSMUSP00000139452	Taste receptor type 2 member 143; Putative taste receptor which may play a role in the perception of bitterness.	Small integral membrane protein 10-like 1.	0.610
Tmem254a	Smim10l1	ENSMUSP00000098374	ENSMUSP00000139452	Transmembrane protein 254a.	Small integral membrane protein 10-like 1.	0.475
Tmem254a	Tmem254b	ENSMUSP00000098374	ENSMUSP00000098369	Transmembrane protein 254a.	Transmembrane protein 254.	0.534
Tmem254b	Smim10l1	ENSMUSP00000098369	ENSMUSP00000139452	Transmembrane protein 254.	Small integral membrane protein 10-like 1.	0.415
Tmem254b	Tmem254a	ENSMUSP00000098369	ENSMUSP00000098374	Transmembrane protein 254.	Transmembrane protein 254a.	0.534