node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Atox1 | Ccs | ENSMUSP00000104485 | ENSMUSP00000035486 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). | 0.917 |
Atox1 | Sod3 | ENSMUSP00000104485 | ENSMUSP00000098768 | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | Extracellular superoxide dismutase [Cu-Zn]; Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. | 0.936 |
Cat | Gpx1 | ENSMUSP00000028610 | ENSMUSP00000081010 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | 0.547 |
Cat | Gpx2 | ENSMUSP00000028610 | ENSMUSP00000081012 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. | Glutathione peroxidase 2. | 0.504 |
Cat | Gpx3 | ENSMUSP00000028610 | ENSMUSP00000081011 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. | Glutathione peroxidase 3; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. | 0.513 |
Cat | Gpx7 | ENSMUSP00000028610 | ENSMUSP00000030332 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. | Glutathione peroxidase 7; It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks (By similarity). | 0.607 |
Cat | Gpx8 | ENSMUSP00000028610 | ENSMUSP00000022282 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. | Probable glutathione peroxidase 8; Belongs to the glutathione peroxidase family. | 0.609 |
Cat | Park7 | ENSMUSP00000028610 | ENSMUSP00000101299 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. | Protein/nucleic acid deglycase DJ-1; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminoca [...] | 0.694 |
Cat | Sod2 | ENSMUSP00000028610 | ENSMUSP00000007012 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. | Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family. | 0.810 |
Cat | Sod3 | ENSMUSP00000028610 | ENSMUSP00000098768 | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. | Extracellular superoxide dismutase [Cu-Zn]; Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. | 0.790 |
Ccs | Atox1 | ENSMUSP00000035486 | ENSMUSP00000104485 | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). | Copper transport protein ATOX1; Binds and deliver cytosolic copper to the copper ATPase proteins. May be important in cellular antioxidant defense (By similarity); Belongs to the ATX1 family. | 0.917 |
Ccs | Gpx1 | ENSMUSP00000035486 | ENSMUSP00000081010 | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | 0.606 |
Ccs | Gpx2 | ENSMUSP00000035486 | ENSMUSP00000081012 | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). | Glutathione peroxidase 2. | 0.495 |
Ccs | Gpx3 | ENSMUSP00000035486 | ENSMUSP00000081011 | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). | Glutathione peroxidase 3; Protects cells and enzymes from oxidative damage, by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxide, by glutathione. | 0.550 |
Ccs | Gpx7 | ENSMUSP00000035486 | ENSMUSP00000030332 | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). | Glutathione peroxidase 7; It protects esophageal epithelia from hydrogen peroxide- induced oxidative stress. It suppresses acidic bile acid-induced reactive oxigen species (ROS) and protects against oxidative DNA damage and double-strand breaks (By similarity). | 0.525 |
Ccs | Gpx8 | ENSMUSP00000035486 | ENSMUSP00000022282 | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). | Probable glutathione peroxidase 8; Belongs to the glutathione peroxidase family. | 0.492 |
Ccs | Park7 | ENSMUSP00000035486 | ENSMUSP00000101299 | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). | Protein/nucleic acid deglycase DJ-1; Protein and nucleotide deglycase that catalyzes the deglycation of the Maillard adducts formed between amino groups of proteins or nucleotides and reactive carbonyl groups of glyoxals. Thus, functions as a protein deglycase that repairs methylglyoxal- and glyoxal-glycated proteins, and releases repaired proteins and lactate or glycolate, respectively. Deglycates cysteine, arginine and lysine residues in proteins, and thus reactivates these proteins by reversing glycation by glyoxals. Acts on early glycation intermediates (hemithioacetals and aminoca [...] | 0.401 |
Ccs | Sod2 | ENSMUSP00000035486 | ENSMUSP00000007012 | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). | Superoxide dismutase [Mn], mitochondrial; Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems; Belongs to the iron/manganese superoxide dismutase family. | 0.623 |
Ccs | Sod3 | ENSMUSP00000035486 | ENSMUSP00000098768 | Copper chaperone for superoxide dismutase; Delivers copper to copper zinc superoxide dismutase (SOD1). | Extracellular superoxide dismutase [Cu-Zn]; Protect the extracellular space from toxic effect of reactive oxygen intermediates by converting superoxide radicals into hydrogen peroxide and oxygen. | 0.917 |
Gpx1 | Cat | ENSMUSP00000081010 | ENSMUSP00000028610 | Glutathione peroxidase 1; Protects the hemoglobin in erythrocytes from oxidative breakdown. | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Promotes growth of cells; Belongs to the catalase family. | 0.547 |