STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Skint4Selection and upkeep of intraepithelial T-cells protein 4; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus. (482 aa)    
Predicted Functional Partners:
Skint9
Selection and upkeep of intraepithelial T-cells protein 9; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus; Belongs to the SKINT family.
   
  
0.752
Skint3
Selection and upkeep of intraepithelial T-cells protein 3; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus.
  
  
0.683
Rdh1
Retinol dehydrogenase 1 (All trans); Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
    0.583
Tmprss11b
Transmembrane protease serine 11B-like protein; Serine protease; Belongs to the peptidase S1 family.
   
  
 0.516
Tas2r120
Taste receptor type 2 member 120; Putative taste receptor which may play a role in the perception of bitterness.
      
 0.442
Tas2r103
Taste receptor type 2 member 103; Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5.
      
 0.432
Sprr2e
Small proline-rich protein 2E; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity).
      
 0.432
Skint8
Selection and upkeep of intraepithelial T-cells protein 8; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus.
  
  
0.412
Sprr2b
Small proline-rich protein 2B; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity).
      
 0.410
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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