node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Myh3 | Myl1 | ENSMUSP00000104329 | ENSMUSP00000027151 | Myosin-3; Muscle contraction. | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | 0.921 |
Myh3 | Myl3 | ENSMUSP00000104329 | ENSMUSP00000078715 | Myosin-3; Muscle contraction. | Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium. | 0.876 |
Myh3 | Myl4 | ENSMUSP00000104329 | ENSMUSP00000102570 | Myosin-3; Muscle contraction. | Myosin light chain 4; Regulatory light chain of myosin. Does not bind calcium. | 0.906 |
Myh3 | Mylpf | ENSMUSP00000104329 | ENSMUSP00000032910 | Myosin-3; Muscle contraction. | Myosin regulatory light chain 2, skeletal muscle isoform. | 0.861 |
Myh3 | Myog | ENSMUSP00000104329 | ENSMUSP00000027730 | Myosin-3; Muscle contraction. | Myogenin; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast dif [...] | 0.879 |
Myh3 | Tnnc2 | ENSMUSP00000104329 | ENSMUSP00000099384 | Myosin-3; Muscle contraction. | Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. | 0.871 |
Myh3 | Tnni1 | ENSMUSP00000104329 | ENSMUSP00000123509 | Myosin-3; Muscle contraction. | Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.906 |
Myh3 | Tnni2 | ENSMUSP00000104329 | ENSMUSP00000122733 | Myosin-3; Muscle contraction. | Troponin I, fast skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.920 |
Myh3 | Tnnt1 | ENSMUSP00000104329 | ENSMUSP00000104228 | Myosin-3; Muscle contraction. | Troponin T, slow skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.860 |
Myh3 | Tnnt3 | ENSMUSP00000104329 | ENSMUSP00000136278 | Myosin-3; Muscle contraction. | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.890 |
Myl1 | Myh3 | ENSMUSP00000027151 | ENSMUSP00000104329 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Myosin-3; Muscle contraction. | 0.921 |
Myl1 | Myl3 | ENSMUSP00000027151 | ENSMUSP00000078715 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium. | 0.677 |
Myl1 | Myl4 | ENSMUSP00000027151 | ENSMUSP00000102570 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Myosin light chain 4; Regulatory light chain of myosin. Does not bind calcium. | 0.626 |
Myl1 | Mylpf | ENSMUSP00000027151 | ENSMUSP00000032910 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Myosin regulatory light chain 2, skeletal muscle isoform. | 0.996 |
Myl1 | Myog | ENSMUSP00000027151 | ENSMUSP00000027730 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Myogenin; Acts as a transcriptional activator that promotes transcription of muscle-specific target genes and plays a role in muscle differentiation, cell cycle exit and muscle atrophy. Essential for the development of functional embryonic skeletal fiber muscle differentiation. However is dispensable for postnatal skeletal muscle growth; phosphorylation by CAMK2G inhibits its transcriptional activity in respons to muscle activity. Required for the recruitment of the FACT complex to muscle-specific promoter regions, thus promoting gene expression initiation. During terminal myoblast dif [...] | 0.646 |
Myl1 | Tnnc2 | ENSMUSP00000027151 | ENSMUSP00000099384 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. | 0.951 |
Myl1 | Tnni1 | ENSMUSP00000027151 | ENSMUSP00000123509 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Troponin I, slow skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.944 |
Myl1 | Tnni2 | ENSMUSP00000027151 | ENSMUSP00000122733 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Troponin I, fast skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.974 |
Myl1 | Tnnt1 | ENSMUSP00000027151 | ENSMUSP00000104228 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Troponin T, slow skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.914 |
Myl1 | Tnnt3 | ENSMUSP00000027151 | ENSMUSP00000136278 | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.976 |