node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Htt | Snap25 | ENSMUSP00000078945 | ENSMUSP00000028727 | Huntingtin, myristoylated N-terminal fragment; [Huntingtin]: May play a role in microtubule-mediated transport or vesicle function. | Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells (By similarity). | 0.702 |
Htt | Zdhhc13 | ENSMUSP00000078945 | ENSMUSP00000112498 | Huntingtin, myristoylated N-terminal fragment; [Huntingtin]: May play a role in microtubule-mediated transport or vesicle function. | Palmitoyltransferase ZDHHC13; Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport. Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily. | 0.913 |
Ppt1 | Snap25 | ENSMUSP00000030412 | ENSMUSP00000028727 | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. | Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells (By similarity). | 0.501 |
Ppt1 | Zdhhc1 | ENSMUSP00000030412 | ENSMUSP00000148381 | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. | Probable palmitoyltransferase ZDHHC1; Belongs to the DHHC palmitoyltransferase family. | 0.581 |
Ppt1 | Zdhhc11 | ENSMUSP00000030412 | ENSMUSP00000089075 | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. | Probable palmitoyltransferase ZDHHC11. | 0.559 |
Ppt1 | Zdhhc13 | ENSMUSP00000030412 | ENSMUSP00000112498 | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. | Palmitoyltransferase ZDHHC13; Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport. Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily. | 0.636 |
Ppt1 | Zdhhc3 | ENSMUSP00000030412 | ENSMUSP00000117392 | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. | Palmitoyltransferase ZDHHC3; Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability. Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi. May also palmitoylate DLG4, DNAJC5 and SNAP25. | 0.533 |
Ppt1 | Zdhhc6 | ENSMUSP00000030412 | ENSMUSP00000076157 | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. | Palmitoyltransferase ZDHHC6; Endoplasmic reticulum palmitoyl acyltransferase that mediates palmitoylation of proteins such as AMFR, CALX, ITPR1 and TFRC. Palmitoylates calnexin (CALX), which is required for its association with the ribosome-translocon complex and efficient folding of glycosylated proteins (By similarity). Mediates palmitoylation of AMFR, promoting AMFR distribution to the peripheral endoplasmic reticulum (By similarity). Together with SELENOK, palmitoylates ITPR1 in immune cells, leading to regulate ITPR1 stability and function. Belongs to the DHHC palmitoyltransferase [...] | 0.537 |
Ppt1 | Zdhhc8 | ENSMUSP00000030412 | ENSMUSP00000076224 | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. | Probable palmitoyltransferase ZDHHC8; Palmitoyltransferase involved in glutamatergic transmission. Mediates palmitoylation of ABCA1; Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily. | 0.534 |
Snap25 | Htt | ENSMUSP00000028727 | ENSMUSP00000078945 | Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells (By similarity). | Huntingtin, myristoylated N-terminal fragment; [Huntingtin]: May play a role in microtubule-mediated transport or vesicle function. | 0.702 |
Snap25 | Ppt1 | ENSMUSP00000028727 | ENSMUSP00000030412 | Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells (By similarity). | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. | 0.501 |
Snap25 | Zdhhc13 | ENSMUSP00000028727 | ENSMUSP00000112498 | Synaptosomal-associated protein 25; t-SNARE involved in the molecular regulation of neurotransmitter release. May play an important role in the synaptic function of specific neuronal systems. Associates with proteins involved in vesicle docking and membrane fusion. Regulates plasma membrane recycling through its interaction with CENPF. Modulates the gating characteristics of the delayed rectifier voltage-dependent potassium channel KCNB1 in pancreatic beta cells (By similarity). | Palmitoyltransferase ZDHHC13; Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport. Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily. | 0.725 |
Zdhhc1 | Ppt1 | ENSMUSP00000148381 | ENSMUSP00000030412 | Probable palmitoyltransferase ZDHHC1; Belongs to the DHHC palmitoyltransferase family. | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. | 0.581 |
Zdhhc1 | Zdhhc13 | ENSMUSP00000148381 | ENSMUSP00000112498 | Probable palmitoyltransferase ZDHHC1; Belongs to the DHHC palmitoyltransferase family. | Palmitoyltransferase ZDHHC13; Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport. Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily. | 0.681 |
Zdhhc1 | Zdhhc22 | ENSMUSP00000148381 | ENSMUSP00000152660 | Probable palmitoyltransferase ZDHHC1; Belongs to the DHHC palmitoyltransferase family. | Palmitoyltransferase ZDHHC22; Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane (By similarity). Might also mediate palmitoylation of CNN3. | 0.652 |
Zdhhc1 | Zdhhc3 | ENSMUSP00000148381 | ENSMUSP00000117392 | Probable palmitoyltransferase ZDHHC1; Belongs to the DHHC palmitoyltransferase family. | Palmitoyltransferase ZDHHC3; Palmitoyltransferase with broad specificity. Palmitoylates GABA receptors on their gamma subunit (GABRG1, GABRG2 and GABRG3), which regulates synaptic clustering and/or cell surface stability. Palmitoylates glutamate receptors GRIA1 and GRIA2, which leads to their retention in Golgi. May also palmitoylate DLG4, DNAJC5 and SNAP25. | 0.438 |
Zdhhc1 | Zdhhc8 | ENSMUSP00000148381 | ENSMUSP00000076224 | Probable palmitoyltransferase ZDHHC1; Belongs to the DHHC palmitoyltransferase family. | Probable palmitoyltransferase ZDHHC8; Palmitoyltransferase involved in glutamatergic transmission. Mediates palmitoylation of ABCA1; Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily. | 0.411 |
Zdhhc11 | Ppt1 | ENSMUSP00000089075 | ENSMUSP00000030412 | Probable palmitoyltransferase ZDHHC11. | Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons. | 0.559 |
Zdhhc11 | Zdhhc13 | ENSMUSP00000089075 | ENSMUSP00000112498 | Probable palmitoyltransferase ZDHHC11. | Palmitoyltransferase ZDHHC13; Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport. Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily. | 0.719 |
Zdhhc11 | Zdhhc22 | ENSMUSP00000089075 | ENSMUSP00000152660 | Probable palmitoyltransferase ZDHHC11. | Palmitoyltransferase ZDHHC22; Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane (By similarity). Might also mediate palmitoylation of CNN3. | 0.726 |