STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmub2Transmembrane and ubiquitin-like domain containing 2 (319 aa)    
Predicted Functional Partners:
Thsd7a
Thrombospondin type-1 domain-containing protein 7A; The soluble form promotes endothelial cell migration and filopodia formationduring angiogenesis via a FAK-dependent mechanism
    
   0.667
Rsad1
Radical S-adenosyl methionine domain-containing protein 1, mitochondrial; May be involved in porphyrin cofactor biosynthesis
      
 0.612
Vmn1r231
Vomeronasal 1 receptor 231
      
 0.580
Vmn1r71
Vomeronasal 1 receptor 71
      
 0.550
Ebpl
Emopamil-binding protein-like; Does not possess sterol isomerase activity and does not bind sigma ligands
      
 0.542
Tmem53
Transmembrane protein 53; Belongs to the TMEM53 family
   
  
 0.531
Zdhhc25
Palmitoyltransferase; Zinc finger, DHHC domain containing 25; Belongs to the DHHC palmitoyltransferase family
      
 0.530
Rasgef1c
Ras-GEF domain-containing family member 1C; Guanine nucleotide exchange factor (GEF)
      
 0.529
Zzz3
ZZ-type zinc finger-containing protein 3; Component of the ATAC complex, a complex with histone acetyltransferase activity on histones H3 and H4
      
 0.524
Gpatch3
G patch domain-containing protein 3; Involved in transcriptional regulation. It is able to activate transcription from CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6
      
 0.515
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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