node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Akap4 | Cfap43 | ENSMUSP00000050962 | ENSMUSP00000125007 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility. | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP43 family. | 0.557 |
Akap4 | Cfap44 | ENSMUSP00000050962 | ENSMUSP00000097331 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility. | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP44 family. | 0.631 |
Akap4 | Cfap69 | ENSMUSP00000050962 | ENSMUSP00000053206 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility. | Cilia- and flagella-associated protein 69; Cilium- and flagellum-associated protein. In the olfactory epithelium, regulates the speed of activation and termination of the odor response and thus contributes to the robustness of olfactory transduction pathways. Required for sperm flagellum assembly and stability. | 0.605 |
Akap4 | Dnah1 | ENSMUSP00000050962 | ENSMUSP00000043281 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility. | Dynein heavy chain 1, axonemal; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity). Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme (By similarity). | 0.577 |
Akap4 | Fsip2 | ENSMUSP00000050962 | ENSMUSP00000120314 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility. | Fibrous sheath-interacting protein 2; Plays a role in spermatogenesis. | 0.797 |
Akap4 | Qrich2 | ENSMUSP00000050962 | ENSMUSP00000091437 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility. | Glutamine-rich protein 2; Has an essential role in the formation of sperm flagella and flagellar structure maintainance. It acts as a suppressor of ubiquitination and degradation of proteins involved in flagellar development and motility. | 0.570 |
Akap4 | Spef2 | ENSMUSP00000050962 | ENSMUSP00000035762 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility. | Sperm flagellar protein 2; Required for correct axoneme development in spermatozoa. Important for normal development of the manchette and sperm head morphology. Essential for male fertility. Plays a role in localization of the intraflagellar transport protein IFT20 to the manchette, suggesting function as an adapter for dynein-mediated protein transport during spermatogenesis. Also plays a role in bone growth where it seems to be required for normal osteoblast differentiation. | 0.460 |
Akap4 | Ttc21a | ENSMUSP00000050962 | ENSMUSP00000035100 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility. | Tetratricopeptide repeat protein 21A; Intraflagellar transport (IFT)-associated protein required for spermatogenesis. Required for sperm flagellar formation and intraflagellar transport. Belongs to the TTC21 family. | 0.464 |
Akap4 | Ttc29 | ENSMUSP00000050962 | ENSMUSP00000041919 | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility. | Tetratricopeptide repeat protein 29. | 0.429 |
Cfap43 | Akap4 | ENSMUSP00000125007 | ENSMUSP00000050962 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP43 family. | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility. | 0.557 |
Cfap43 | Cfap44 | ENSMUSP00000125007 | ENSMUSP00000097331 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP43 family. | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP44 family. | 0.720 |
Cfap43 | Cfap69 | ENSMUSP00000125007 | ENSMUSP00000053206 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP43 family. | Cilia- and flagella-associated protein 69; Cilium- and flagellum-associated protein. In the olfactory epithelium, regulates the speed of activation and termination of the odor response and thus contributes to the robustness of olfactory transduction pathways. Required for sperm flagellum assembly and stability. | 0.819 |
Cfap43 | Dnah1 | ENSMUSP00000125007 | ENSMUSP00000043281 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP43 family. | Dynein heavy chain 1, axonemal; Force generating protein of cilia required for sperm flagellum motility. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP (By similarity). Required in spermatozoa for the formation of the inner dynein arms and biogenesis of the axoneme (By similarity). | 0.769 |
Cfap43 | Fsip2 | ENSMUSP00000125007 | ENSMUSP00000120314 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP43 family. | Fibrous sheath-interacting protein 2; Plays a role in spermatogenesis. | 0.742 |
Cfap43 | Qrich2 | ENSMUSP00000125007 | ENSMUSP00000091437 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP43 family. | Glutamine-rich protein 2; Has an essential role in the formation of sperm flagella and flagellar structure maintainance. It acts as a suppressor of ubiquitination and degradation of proteins involved in flagellar development and motility. | 0.825 |
Cfap43 | Spef2 | ENSMUSP00000125007 | ENSMUSP00000035762 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP43 family. | Sperm flagellar protein 2; Required for correct axoneme development in spermatozoa. Important for normal development of the manchette and sperm head morphology. Essential for male fertility. Plays a role in localization of the intraflagellar transport protein IFT20 to the manchette, suggesting function as an adapter for dynein-mediated protein transport during spermatogenesis. Also plays a role in bone growth where it seems to be required for normal osteoblast differentiation. | 0.791 |
Cfap43 | Ttc21a | ENSMUSP00000125007 | ENSMUSP00000035100 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP43 family. | Tetratricopeptide repeat protein 21A; Intraflagellar transport (IFT)-associated protein required for spermatogenesis. Required for sperm flagellar formation and intraflagellar transport. Belongs to the TTC21 family. | 0.788 |
Cfap43 | Ttc29 | ENSMUSP00000125007 | ENSMUSP00000041919 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP43 family. | Tetratricopeptide repeat protein 29. | 0.801 |
Cfap43 | Wdr66 | ENSMUSP00000125007 | ENSMUSP00000113309 | Cilia- and flagella-associated protein 43; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP43 family. | Cilia- and flagella-associated protein 251; Involved in spermatozoa motility (By similarity). May also regulate cilium motility through its role in the assembly of the axonemal radial spokes (By similarity). | 0.832 |
Cfap44 | Akap4 | ENSMUSP00000097331 | ENSMUSP00000050962 | Cilia- and flagella-associated protein 44; Flagellar protein involved in sperm flagellum axoneme organization and function; Belongs to the CFAP44 family. | A-kinase anchor protein 4; Major structural component of sperm fibrous sheath. Plays a role in sperm motility. | 0.631 |