STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BC048679cDNA sequence BC048679. (172 aa)    
Predicted Functional Partners:
C130074G19Rik
Uncharacterized protein C1orf115 homolog.
      
 0.606
Gm21830
Predicted gene, 21830.
      
 0.606
1600014C10Rik
Protein C19orf12 homolog.
      
 0.604
Sbk3
Uncharacterized serine/threonine-protein kinase SBK3.
      
 0.530
Gm10260
Ribosomal protein S18, pseudogene 6; Belongs to the universal ribosomal protein uS13 family.
      
 0.511
Tm6sf1
Transmembrane 6 superfamily member 1; May function as sterol isomerase.
      
 0.485
Armcx4
Armadillo repeat-containing, X-linked 4.
      
 0.439
Hyal3
Hyaluronidase-3; Facilitates sperm penetration into the layer of cumulus cells surrounding the egg by digesting hyaluronic acid. Involved in induction of the acrosome reaction in the sperm. Involved in follicular atresia, the breakdown of immature ovarian follicles that are not selected to ovulate. Induces ovarian granulosa cell apoptosis, possibly via apoptotic signaling pathway involving CASP8 and CASP3 activation, and poly(ADP-ribose) polymerase (PARP) cleavage. Has no hyaluronidase activity in embryonic fibroblasts in vitro. Has no hyaluronidase activity in granulosa cells in vitro [...]
      
 0.410
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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