node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Chd6 | Gpatch8 | ENSMUSP00000042291 | ENSMUSP00000120649 | Chromodomain-helicase-DNA-binding protein 6; DNA-dependent ATPase that plays a role in chromatin remodeling. Regulates transcription by disrupting nucleosomes in a largely non-sliding manner which strongly increases the accessibility of chromatin. Activates transcription of specific genes in response to oxidative stress through interaction with NFE2L2. | G patch domain-containing protein 8. | 0.606 |
Ddx10 | Gpatch8 | ENSMUSP00000065198 | ENSMUSP00000120649 | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase. | G patch domain-containing protein 8. | 0.556 |
Ddx10 | Krr1 | ENSMUSP00000065198 | ENSMUSP00000125746 | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase. | KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | 0.813 |
Ddx10 | Nol6 | ENSMUSP00000065198 | ENSMUSP00000030138 | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase. | Nucleolar protein 6; Belongs to the NRAP family. | 0.975 |
Ddx10 | Nom1 | ENSMUSP00000065198 | ENSMUSP00000001611 | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase. | Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus. | 0.983 |
Ddx10 | Rrp36 | ENSMUSP00000065198 | ENSMUSP00000024766 | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase. | Ribosomal RNA processing protein 36 homolog; Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA; Belongs to the RRP36 family. | 0.978 |
Ddx10 | Utp6 | ENSMUSP00000065198 | ENSMUSP00000046643 | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase. | U3 small nucleolar RNA-associated protein 6 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the UTP6 family. | 0.723 |
Gpatch8 | Chd6 | ENSMUSP00000120649 | ENSMUSP00000042291 | G patch domain-containing protein 8. | Chromodomain-helicase-DNA-binding protein 6; DNA-dependent ATPase that plays a role in chromatin remodeling. Regulates transcription by disrupting nucleosomes in a largely non-sliding manner which strongly increases the accessibility of chromatin. Activates transcription of specific genes in response to oxidative stress through interaction with NFE2L2. | 0.606 |
Gpatch8 | Ddx10 | ENSMUSP00000120649 | ENSMUSP00000065198 | G patch domain-containing protein 8. | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase. | 0.556 |
Gpatch8 | Kmt2e | ENSMUSP00000120649 | ENSMUSP00000110781 | G patch domain-containing protein 8. | Inactive histone-lysine N-methyltransferase 2E; Associates with chromatin regions downstream of transcriptional start sites of active genes and thus regulates gene transcription (By similarity). Chromatin interaction is mediated via the binding to tri-methylated histone H3 at 'Lys-4' (H3K4me3) (By similarity). Key regulator of hematopoiesis involved in terminal myeloid differentiation and in the regulation of hematopoietic stem cell (HSCs) self-renewal by a mechanism that involves DNA methylation. Also acts as an important cell cycle regulator, participating in cell cycle regulatory ne [...] | 0.543 |
Gpatch8 | Krr1 | ENSMUSP00000120649 | ENSMUSP00000125746 | G patch domain-containing protein 8. | KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | 0.646 |
Gpatch8 | Nol6 | ENSMUSP00000120649 | ENSMUSP00000030138 | G patch domain-containing protein 8. | Nucleolar protein 6; Belongs to the NRAP family. | 0.548 |
Gpatch8 | Nom1 | ENSMUSP00000120649 | ENSMUSP00000001611 | G patch domain-containing protein 8. | Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus. | 0.549 |
Gpatch8 | Prpf4b | ENSMUSP00000120649 | ENSMUSP00000077019 | G patch domain-containing protein 8. | Serine/threonine-protein kinase PRP4 homolog; Has a role in pre-mRNA splicing. Phosphorylates SF2/ASF; Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. | 0.601 |
Gpatch8 | Rnf20 | ENSMUSP00000120649 | ENSMUSP00000128546 | G patch domain-containing protein 8. | E3 ubiquitin-protein ligase BRE1A; Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of 'Lys-120' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 'Lys-4' and 'Lys-79' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role in histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B; reports about the cooperation with UBE2E1/UBCH are contradic [...] | 0.592 |
Gpatch8 | Rrp36 | ENSMUSP00000120649 | ENSMUSP00000024766 | G patch domain-containing protein 8. | Ribosomal RNA processing protein 36 homolog; Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA; Belongs to the RRP36 family. | 0.542 |
Gpatch8 | Utp6 | ENSMUSP00000120649 | ENSMUSP00000046643 | G patch domain-containing protein 8. | U3 small nucleolar RNA-associated protein 6 homolog; Involved in nucleolar processing of pre-18S ribosomal RNA. Belongs to the UTP6 family. | 0.553 |
Kmt2e | Gpatch8 | ENSMUSP00000110781 | ENSMUSP00000120649 | Inactive histone-lysine N-methyltransferase 2E; Associates with chromatin regions downstream of transcriptional start sites of active genes and thus regulates gene transcription (By similarity). Chromatin interaction is mediated via the binding to tri-methylated histone H3 at 'Lys-4' (H3K4me3) (By similarity). Key regulator of hematopoiesis involved in terminal myeloid differentiation and in the regulation of hematopoietic stem cell (HSCs) self-renewal by a mechanism that involves DNA methylation. Also acts as an important cell cycle regulator, participating in cell cycle regulatory ne [...] | G patch domain-containing protein 8. | 0.543 |
Krr1 | Ddx10 | ENSMUSP00000125746 | ENSMUSP00000065198 | KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | Probable ATP-dependent RNA helicase DDX10; Putative ATP-dependent RNA helicase. | 0.813 |
Krr1 | Gpatch8 | ENSMUSP00000125746 | ENSMUSP00000120649 | KRR1 small subunit processome component homolog; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly (By similarity). | G patch domain-containing protein 8. | 0.646 |