STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Zfp26Zinc finger protein 26; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. (959 aa)    
Predicted Functional Partners:
Zfp512b
Zinc finger protein 512B.
   
 
 0.636
9330182L06Rik
UPF0577 protein KIAA1324-like homolog; Belongs to the UPF0577 family.
    
 
 0.563
Zfp608
Zinc finger protein 608; Transcription factor, which represses ZNF609 transcription.
   
  
 0.536
Ammecr1l
AMMECR1-like protein.
   
  
 0.527
Trim28
Transcription intermediary factor 1-beta; Nuclear corepressor for KRAB domain-containing zinc finger proteins (KRAB-ZFPs). Mediates gene silencing by recruiting CHD3, a subunit of the nucleosome remodeling and deacetylation (NuRD) complex, and SETDB1 (which specifically methylates histone H3 at 'Lys-9' (H3K9me)) to the promoter regions of KRAB target genes. Enhances transcriptional repression by coordinating the increase in H3K9me, the decrease in histone H3 'Lys-9 and 'Lys-14' acetylation (H3K9ac and H3K14ac, respectively) and the disposition of HP1 proteins to silence gene expression [...]
   
  0.524
Trex2
Three prime repair exonuclease 2; Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair.
    
 
 0.497
Borcs7
BLOC-1-related complex subunit 7; As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor.
    
 
 0.446
Tmem198b
Transmembrane protein 198b.
   
  
 0.413
Pogk
Pogo transposable element with KRAB domain.
   
 
 0.406
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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