node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
A930017K11Rik | Ccdc36 | ENSMUSP00000125106 | ENSMUSP00000075898 | RIKEN cDNA A930017K11 gene. | Interactor of HORMAD1 protein 1; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance. | 0.482 |
A930017K11Rik | Kbtbd12 | ENSMUSP00000125106 | ENSMUSP00000112581 | RIKEN cDNA A930017K11 gene. | Kelch repeat and BTB domain-containing protein 12. | 0.514 |
A930017K11Rik | Kcng3 | ENSMUSP00000125106 | ENSMUSP00000054910 | RIKEN cDNA A930017K11 gene. | Potassium voltage-gated channel subfamily G member 3; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1. | 0.490 |
A930017K11Rik | Nhlrc4 | ENSMUSP00000125106 | ENSMUSP00000082102 | RIKEN cDNA A930017K11 gene. | NHL-repeat-containing protein 4. | 0.631 |
A930017K11Rik | Rab11fip3 | ENSMUSP00000125106 | ENSMUSP00000113521 | RIKEN cDNA A930017K11 gene. | Rab11 family-interacting protein 3; Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis (By similarity). Also required for the structural integrity of the endosomal recycling compartment during interphase. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facili [...] | 0.461 |
A930017K11Rik | Rrp36 | ENSMUSP00000125106 | ENSMUSP00000024766 | RIKEN cDNA A930017K11 gene. | Ribosomal RNA processing protein 36 homolog; Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA; Belongs to the RRP36 family. | 0.514 |
A930017K11Rik | Sipa1l2 | ENSMUSP00000125106 | ENSMUSP00000148536 | RIKEN cDNA A930017K11 gene. | Signal-induced proliferation-associated 1-like protein 2. | 0.461 |
A930017K11Rik | Togaram1 | ENSMUSP00000125106 | ENSMUSP00000070382 | RIKEN cDNA A930017K11 gene. | TOG array regulator of axonemal microtubules protein 1; Required for normal structure and function of primary cilia. Plays a role in the organization of axoneme microtubule bundles in primary cilia (By similarity). Interacts with microtubules and promotes microtubule polymerization via its HEAT repeat domains, especially those in TOG region 2 and 4. Belongs to the Crescerin family. | 0.461 |
A930017K11Rik | Trappc6b | ENSMUSP00000125106 | ENSMUSP00000021380 | RIKEN cDNA A930017K11 gene. | Trafficking protein particle complex subunit 6B; Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic (By similarity). Specifically involved in the early development of neural circuitry, likely by controlling the frequency and amplitude of intracellular calcium transients implicated in the regulation of neuron differentiation and survival (By similarity). Belongs to the TRAPP small subunits family. BET3 subfamily. | 0.461 |
A930017K11Rik | Vwc2 | ENSMUSP00000125106 | ENSMUSP00000105303 | RIKEN cDNA A930017K11 gene. | Brorin; BMP antagonist which may play a role in neural development. Promotes cell adhesion. | 0.453 |
Ccdc36 | A930017K11Rik | ENSMUSP00000075898 | ENSMUSP00000125106 | Interactor of HORMAD1 protein 1; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance. | RIKEN cDNA A930017K11 gene. | 0.482 |
Ccdc36 | Kbtbd12 | ENSMUSP00000075898 | ENSMUSP00000112581 | Interactor of HORMAD1 protein 1; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance. | Kelch repeat and BTB domain-containing protein 12. | 0.642 |
Ccdc36 | Kcng3 | ENSMUSP00000075898 | ENSMUSP00000054910 | Interactor of HORMAD1 protein 1; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance. | Potassium voltage-gated channel subfamily G member 3; Potassium channel subunit that does not form functional channels by itself. Can form functional heterotetrameric channels with KCNB1; modulates the delayed rectifier voltage-gated potassium channel activation and deactivation rates of KCNB1. | 0.558 |
Ccdc36 | Rab11fip3 | ENSMUSP00000075898 | ENSMUSP00000113521 | Interactor of HORMAD1 protein 1; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance. | Rab11 family-interacting protein 3; Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis (By similarity). Also required for the structural integrity of the endosomal recycling compartment during interphase. Acts as an adapter protein linking the dynein motor complex to various cargos and converts dynein from a non-processive to a highly processive motor in the presence of dynactin. Facili [...] | 0.476 |
Ccdc36 | Rrp36 | ENSMUSP00000075898 | ENSMUSP00000024766 | Interactor of HORMAD1 protein 1; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance. | Ribosomal RNA processing protein 36 homolog; Involved in the early processing steps of the pre-rRNA in the maturation pathway leading to the 18S rRNA; Belongs to the RRP36 family. | 0.634 |
Ccdc36 | Sipa1l2 | ENSMUSP00000075898 | ENSMUSP00000148536 | Interactor of HORMAD1 protein 1; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance. | Signal-induced proliferation-associated 1-like protein 2. | 0.554 |
Ccdc36 | Togaram1 | ENSMUSP00000075898 | ENSMUSP00000070382 | Interactor of HORMAD1 protein 1; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance. | TOG array regulator of axonemal microtubules protein 1; Required for normal structure and function of primary cilia. Plays a role in the organization of axoneme microtubule bundles in primary cilia (By similarity). Interacts with microtubules and promotes microtubule polymerization via its HEAT repeat domains, especially those in TOG region 2 and 4. Belongs to the Crescerin family. | 0.526 |
Ccdc36 | Trappc6b | ENSMUSP00000075898 | ENSMUSP00000021380 | Interactor of HORMAD1 protein 1; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance. | Trafficking protein particle complex subunit 6B; Component of a transport protein particle (TRAPP) complex that may function in specific stages of inter-organelle traffic (By similarity). Specifically involved in the early development of neural circuitry, likely by controlling the frequency and amplitude of intracellular calcium transients implicated in the regulation of neuron differentiation and survival (By similarity). Belongs to the TRAPP small subunits family. BET3 subfamily. | 0.516 |
Ccdc36 | Vwc2 | ENSMUSP00000075898 | ENSMUSP00000105303 | Interactor of HORMAD1 protein 1; Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance. | Brorin; BMP antagonist which may play a role in neural development. Promotes cell adhesion. | 0.470 |
Kbtbd12 | A930017K11Rik | ENSMUSP00000112581 | ENSMUSP00000125106 | Kelch repeat and BTB domain-containing protein 12. | RIKEN cDNA A930017K11 gene. | 0.514 |