STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gfm2Ribosome-releasing factor 2, mitochondrial; Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (779 aa)    
Predicted Functional Partners:
Mrpl27
39S ribosomal protein L27, mitochondrial; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.933
Mrpl12
39S ribosomal protein L12, mitochondrial; Belongs to the bacterial ribosomal protein bL12 family.
   
 
 0.928
Mrpl20
39S ribosomal protein L20, mitochondrial; Belongs to the bacterial ribosomal protein bL20 family.
  
 
 0.926
Mrrf
Ribosome-recycling factor, mitochondrial; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity); Belongs to the RRF family.
   
 
 0.907
Mrpl36
39S ribosomal protein L36, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family.
  
 
 0.880
Mrpl19
39S ribosomal protein L19, mitochondrial; Belongs to the bacterial ribosomal protein bL19 family.
  
 
 0.875
Mrpl58
Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (By similarity).
  
 
 0.873
Mrpl33
39S ribosomal protein L33, mitochondrial; Belongs to the bacterial ribosomal protein bL33 family.
   
 
 0.852
Mrpl9
39S ribosomal protein L9, mitochondrial; Belongs to the bacterial ribosomal protein bL9 family.
   
 
 0.851
Mrpl32
39S ribosomal protein L32, mitochondrial; Belongs to the bacterial ribosomal protein bL32 family.
   
   0.836
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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