node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ermn | Gpr62 | ENSMUSP00000088458 | ENSMUSP00000129055 | Ermin; Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the maintenance and plasticity of related structures in the mature CNS (By similarity). | G-protein coupled receptor 62; Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways. Has spontaneous activity for beta-arrestin recruitment (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity). | 0.505 |
Gpr101 | Gpr162 | ENSMUSP00000058183 | ENSMUSP00000145267 | Probable G-protein coupled receptor 101; Orphan receptor. | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.514 |
Gpr101 | Gpr26 | ENSMUSP00000058183 | ENSMUSP00000041664 | Probable G-protein coupled receptor 101; Orphan receptor. | G-protein coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP (By similarity); Belongs to the G-protein coupled receptor 1 family. | 0.538 |
Gpr101 | Gpr62 | ENSMUSP00000058183 | ENSMUSP00000129055 | Probable G-protein coupled receptor 101; Orphan receptor. | G-protein coupled receptor 62; Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways. Has spontaneous activity for beta-arrestin recruitment (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity). | 0.534 |
Gpr135 | Gpr162 | ENSMUSP00000058762 | ENSMUSP00000145267 | G-protein coupled receptor 135; Orphan receptor. Has spontaneous activity for beta-arrestin recruitment (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity). | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.442 |
Gpr135 | Gpr25 | ENSMUSP00000058762 | ENSMUSP00000083583 | G-protein coupled receptor 135; Orphan receptor. Has spontaneous activity for beta-arrestin recruitment (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity). | Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.411 |
Gpr135 | Gpr62 | ENSMUSP00000058762 | ENSMUSP00000129055 | G-protein coupled receptor 135; Orphan receptor. Has spontaneous activity for beta-arrestin recruitment (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity). | G-protein coupled receptor 62; Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways. Has spontaneous activity for beta-arrestin recruitment (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity). | 0.639 |
Gpr162 | Gpr101 | ENSMUSP00000145267 | ENSMUSP00000058183 | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Probable G-protein coupled receptor 101; Orphan receptor. | 0.514 |
Gpr162 | Gpr135 | ENSMUSP00000145267 | ENSMUSP00000058762 | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | G-protein coupled receptor 135; Orphan receptor. Has spontaneous activity for beta-arrestin recruitment (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity). | 0.442 |
Gpr162 | Gpr25 | ENSMUSP00000145267 | ENSMUSP00000083583 | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.517 |
Gpr162 | Gpr26 | ENSMUSP00000145267 | ENSMUSP00000041664 | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | G-protein coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP (By similarity); Belongs to the G-protein coupled receptor 1 family. | 0.664 |
Gpr162 | Gpr62 | ENSMUSP00000145267 | ENSMUSP00000129055 | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | G-protein coupled receptor 62; Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways. Has spontaneous activity for beta-arrestin recruitment (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity). | 0.565 |
Gpr25 | Gpr135 | ENSMUSP00000083583 | ENSMUSP00000058762 | Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | G-protein coupled receptor 135; Orphan receptor. Has spontaneous activity for beta-arrestin recruitment (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity). | 0.411 |
Gpr25 | Gpr162 | ENSMUSP00000083583 | ENSMUSP00000145267 | Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.517 |
Gpr25 | Gpr62 | ENSMUSP00000083583 | ENSMUSP00000129055 | Probable G-protein coupled receptor 25; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | G-protein coupled receptor 62; Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways. Has spontaneous activity for beta-arrestin recruitment (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity). | 0.554 |
Gpr26 | Gpr101 | ENSMUSP00000041664 | ENSMUSP00000058183 | G-protein coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP (By similarity); Belongs to the G-protein coupled receptor 1 family. | Probable G-protein coupled receptor 101; Orphan receptor. | 0.538 |
Gpr26 | Gpr162 | ENSMUSP00000041664 | ENSMUSP00000145267 | G-protein coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP (By similarity); Belongs to the G-protein coupled receptor 1 family. | Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. | 0.664 |
Gpr26 | Gpr50 | ENSMUSP00000041664 | ENSMUSP00000064608 | G-protein coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP (By similarity); Belongs to the G-protein coupled receptor 1 family. | Melatonin-related receptor; Does not bind melatonin; Belongs to the G-protein coupled receptor 1 family. | 0.400 |
Gpr26 | Gpr62 | ENSMUSP00000041664 | ENSMUSP00000129055 | G-protein coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP (By similarity); Belongs to the G-protein coupled receptor 1 family. | G-protein coupled receptor 62; Orphan G-protein coupled receptor. Constitutively activates the G(q/11)/inositol phosphate and the G(s)-alpha/cAMP signaling pathways. Has spontaneous activity for beta-arrestin recruitment (By similarity). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (By similarity). | 0.554 |
Gpr50 | Gpr26 | ENSMUSP00000064608 | ENSMUSP00000041664 | Melatonin-related receptor; Does not bind melatonin; Belongs to the G-protein coupled receptor 1 family. | G-protein coupled receptor 26; Orphan receptor. Displays a significant level of constitutive activity. Its effect is mediated by G(s)-alpha protein that stimulate adenylate cyclase, resulting in an elevation of intracellular cAMP (By similarity); Belongs to the G-protein coupled receptor 1 family. | 0.400 |