STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Pkhd1l1Fibrocystin-L. (4249 aa)    
Predicted Functional Partners:
Csmd3
CUB and sushi domain-containing protein 3; Involved in dendrite development.
   
  
 0.592
3110021N24Rik
RIKEN cDNA 3110021N24 gene.
      
 0.574
Fam186a
Protein FAM186A.
   
  
 0.526
Gnl1
Guanine nucleotide-binding protein-like 1; Possible regulatory or functional link with the histocompatibility cluster.
      
 0.520
Vsig10l
V-set and immunoglobulin domain-containing protein 10-like.
    
 
 0.515
Cdcp2
CUB domain-containing protein 2.
      
 0.488
Gm12689
Predicted gene 12689.
      
 0.487
Mast4
Microtubule-associated serine/threonine-protein kinase 4.
      
 0.475
Ccdc190
Coiled-coil domain-containing protein 190.
      
 0.472
Ush2a
Usherin; Involved in hearing and vision as member of the USH2 complex. In the inner ear, required for the maintenance of hair bundle ankle formation, which connects growing stereocilia in developing cochlear hair cells. In retina photoreceptors, the USH2 complex is required for the maintenance of periciliary membrane complex that seems to play a role in regulating intracellular protein transport.
   
 
 0.464
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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