node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Acta1 | Myh1 | ENSMUSP00000034453 | ENSMUSP00000117569 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Myosin-1; Muscle contraction. | 0.838 |
Acta1 | Myh2 | ENSMUSP00000034453 | ENSMUSP00000129544 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Myosin, heavy polypeptide 2, skeletal muscle, adult; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.877 |
Acta1 | Myh4 | ENSMUSP00000034453 | ENSMUSP00000018632 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Myosin-4; Muscle contraction. | 0.977 |
Acta1 | Myl1 | ENSMUSP00000034453 | ENSMUSP00000027151 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | 0.980 |
Acta1 | Myl3 | ENSMUSP00000034453 | ENSMUSP00000078715 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium. | 0.700 |
Acta1 | Tnnc2 | ENSMUSP00000034453 | ENSMUSP00000099384 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Troponin C, skeletal muscle; Troponin is the central regulatory protein of striated muscle contraction. Tn consists of three components: Tn-I which is the inhibitor of actomyosin ATPase, Tn-T which contains the binding site for tropomyosin and Tn-C. The binding of calcium to Tn-C abolishes the inhibitory action of Tn on actin filaments. | 0.930 |
Acta1 | Tnni2 | ENSMUSP00000034453 | ENSMUSP00000122733 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Troponin I, fast skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.881 |
Acta1 | Tnnt3 | ENSMUSP00000034453 | ENSMUSP00000136278 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Troponin T, fast skeletal muscle; Troponin T is the tropomyosin-binding subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.864 |
Acta1 | Ttn | ENSMUSP00000034453 | ENSMUSP00000107477 | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | Titin; Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase. | 0.830 |
Gm49909 | Myh1 | ENSMUSP00000156883 | ENSMUSP00000117569 | Predicted gene, 49909. | Myosin-1; Muscle contraction. | 0.835 |
Gm49909 | Myh2 | ENSMUSP00000156883 | ENSMUSP00000129544 | Predicted gene, 49909. | Myosin, heavy polypeptide 2, skeletal muscle, adult; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.847 |
Gm49909 | Myh4 | ENSMUSP00000156883 | ENSMUSP00000018632 | Predicted gene, 49909. | Myosin-4; Muscle contraction. | 0.764 |
Gm49909 | Myl1 | ENSMUSP00000156883 | ENSMUSP00000027151 | Predicted gene, 49909. | Myosin light chain 1/3, skeletal muscle isoform; Non-regulatory myosin light chain required for proper formation and/or maintenance of myofibers, and thus appropriate muscle function. | 0.898 |
Gm49909 | Myl3 | ENSMUSP00000156883 | ENSMUSP00000078715 | Predicted gene, 49909. | Myosin light chain 3; Regulatory light chain of myosin. Does not bind calcium. | 0.810 |
Gm49909 | Tnni2 | ENSMUSP00000156883 | ENSMUSP00000122733 | Predicted gene, 49909. | Troponin I, fast skeletal muscle; Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity. | 0.453 |
Gm49909 | Ttn | ENSMUSP00000156883 | ENSMUSP00000107477 | Predicted gene, 49909. | Titin; Key component in the assembly and functioning of vertebrate striated muscles. By providing connections at the level of individual microfilaments, it contributes to the fine balance of forces between the two halves of the sarcomere. The size and extensibility of the cross-links are the main determinants of sarcomere extensibility properties of muscle. In non-muscle cells, seems to play a role in chromosome condensation and chromosome segregation during mitosis. Might link the lamina network to chromatin or nuclear actin, or both during interphase. | 0.917 |
Myh1 | Acta1 | ENSMUSP00000117569 | ENSMUSP00000034453 | Myosin-1; Muscle contraction. | Actin, alpha skeletal muscle, intermediate form; Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. | 0.838 |
Myh1 | Gm49909 | ENSMUSP00000117569 | ENSMUSP00000156883 | Myosin-1; Muscle contraction. | Predicted gene, 49909. | 0.835 |
Myh1 | Myh2 | ENSMUSP00000117569 | ENSMUSP00000129544 | Myosin-1; Muscle contraction. | Myosin, heavy polypeptide 2, skeletal muscle, adult; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. | 0.977 |
Myh1 | Myh4 | ENSMUSP00000117569 | ENSMUSP00000018632 | Myosin-1; Muscle contraction. | Myosin-4; Muscle contraction. | 0.944 |