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Muc5ac protein (mouse) - STRING interaction network
"Muc5ac" - Mucin 5, subtypes A and C, tracheobronchial/gastric in Mus musculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Muc5acMucin 5, subtypes A and C, tracheobronchial/gastric (2751 aa)    
Predicted Functional Partners:
Muc4
Mucin-4; Mucin 4 (3470 aa)
     
 
  0.981
Muc16
Mucin 16 (258 aa)
     
 
  0.971
Muc13
Mucin-13; Epithelial and hemopoietic transmembrane mucin that may play a role in cell signaling (573 aa)
     
 
  0.968
Muc20
Mucin-20; May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression (By similarity) (688 aa)
         
  0.967
Muc15
Mucin-15; Mucin 15 (331 aa)
         
  0.962
Gm9573
Predicted gene 9573 (1606 aa)
     
 
  0.957
A4gnt
Alpha-1,4-N-acetylglucosaminyltransferase; Catalyzes the transfer of N-acetylglucosamine (GlcNAc) to core 2 branched O-glycans. Necessary for the synthesis of type III mucin which is specifically produced in the stomach, duodenum, and pancreatic duct. May protect against inflammation-associated gastric adenocarcinoma (341 aa)
         
  0.931
Muc3a
Mucin 3A, cell surface-associated; RIKEN cDNA A630081J09 gene (218 aa)
     
 
  0.931
ENSMUSG00000096914
UDP-N-acetyl-alpha-D-galactosamine-polypeptide N-acetylgalactosaminyltransferase-like 6 (417 aa)
       
  0.931
Gcnt4
Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase 4; Glycosyltransferase that mediates core 2 O-glycan branching, an important step in mucin-type biosynthesis. Does not have core 4 O-glycan or I-branching enzyme activity; Belongs to the glycosyltransferase 14 family (455 aa)
         
  0.929
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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