STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Samt1bSpermatogenesis associated multipass transmembrane protein 1b. (237 aa)    
Predicted Functional Partners:
Gm6812
Predicted gene 6812.
   
  
 0.722
H2al3
H2A histone family member L3.
   
  
 0.701
March11
E3 ubiquitin-protein ligase MARCHF11; E3 ubiquitin-protein ligase that mediates polyubiquitination of CD4. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin- conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. May play a role in ubuquitin-dependent protein sorting in developmenting spermatids.
      
 0.665
Rbm31y
RNA-binding motif 31, Y-linked.
   
  
 0.662
Samt1
Spermatogenesis associated multipass transmembrane protein 1.
   
   
0.648
H2al1a
H2A histone family member L1A.
   
  
 0.586
H2ap
Huntingtin-interacting protein M.
   
  
 0.579
Tgif2lx1
TGFB-induced factor homeobox 2-like, X-linked 1.
   
  
 0.573
Tgif2lx2
TGFB-induced factor homeobox 2-like, X-linked 1.
   
  
 0.572
H2al1i
Histone H2A-like 1; Atypical histone H2A which can replace conventional H2A in some nucleosomes and may play a role during spermatogenesis. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
  
 0.530
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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