STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SbpProstatic spermine-binding protein; This protein seems to be functional equivalent to rat prostatic spermine-binding protein, which is involved in polyamine binding. (199 aa)    
Predicted Functional Partners:
Pbsn
Probasin.
   
  
 0.818
Cdcp3
Putative DMBT1-like protein.
   
 
 0.716
Tcaf3
TRPM8 channel-associated factor 3; May play a role in the regulation of the cation channel TRPM8 activity.
      
 0.644
Msmb
Beta-microseminoprotein; Belongs to the beta-microseminoprotein family.
   
  
 0.605
Svs2
Seminal vesicle secretory protein 2.
   
  
 0.589
Tgm4
Protein-glutamine gamma-glutamyltransferase 4; Associated with the mammalian reproductive process. Plays an important role in the formation of the seminal coagulum through the cross-linking of specific proteins present in the seminal plasma. Transglutaminase is also required to stabilize the copulatory plug.
   
  
 0.557
Spink1
Serine protease inhibitor Kazal-type 1; Serine protease inhibitor which exhibits anti-trypsin activity. In the pancreas, protects against trypsin-catalyzed premature activation of zymogens.
   
  
 0.523
Sbpl
Spermine-binding protein-like.
  
   
0.470
Hoxb13
Homeobox protein Hox-B13; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Binds preferentially to methylated DNA (By similarity). Belongs to the Abd-B homeobox family.
   
  
 0.413
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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