Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Casp4 | Gsdmc2 | ENSMUSP00000027012 | ENSMUSP00000140487 | Caspase-4 subunit p10; Proinflammatory caspase. Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non- canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS, as well as infection with Gram-negative bacteria. Independently of NLRP3 inflammasome and CASP1, promotes pyroptosis, through GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators. Plays a crucial role in the restriction of Salmonella typhimurium replication in colonic e [...] | Gasdermin-C2; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | 0.459 |
| Casp4 | Gsdmc3 | ENSMUSP00000027012 | ENSMUSP00000140272 | Caspase-4 subunit p10; Proinflammatory caspase. Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non- canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS, as well as infection with Gram-negative bacteria. Independently of NLRP3 inflammasome and CASP1, promotes pyroptosis, through GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators. Plays a crucial role in the restriction of Salmonella typhimurium replication in colonic e [...] | Gasdermin-C3; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | 0.480 |
| Casp4 | Gsdme | ENSMUSP00000027012 | ENSMUSP00000031845 | Caspase-4 subunit p10; Proinflammatory caspase. Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non- canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS, as well as infection with Gram-negative bacteria. Independently of NLRP3 inflammasome and CASP1, promotes pyroptosis, through GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators. Plays a crucial role in the restriction of Salmonella typhimurium replication in colonic e [...] | Gasdermin-E, C-terminal; Plays a role in the TP53-regulated cellular response to DNA damage probably by cooperating with TP53. | 0.763 |
| Casp4 | Pjvk | ENSMUSP00000027012 | ENSMUSP00000097566 | Caspase-4 subunit p10; Proinflammatory caspase. Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non- canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS, as well as infection with Gram-negative bacteria. Independently of NLRP3 inflammasome and CASP1, promotes pyroptosis, through GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators. Plays a crucial role in the restriction of Salmonella typhimurium replication in colonic e [...] | Pejvakin; Essential in the activity of auditory pathway neurons; Belongs to the gasdermin family. | 0.617 |
| Gsdmc2 | Casp4 | ENSMUSP00000140487 | ENSMUSP00000027012 | Gasdermin-C2; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | Caspase-4 subunit p10; Proinflammatory caspase. Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non- canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS, as well as infection with Gram-negative bacteria. Independently of NLRP3 inflammasome and CASP1, promotes pyroptosis, through GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators. Plays a crucial role in the restriction of Salmonella typhimurium replication in colonic e [...] | 0.459 |
| Gsdmc2 | Gsdmc3 | ENSMUSP00000140487 | ENSMUSP00000140272 | Gasdermin-C2; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | Gasdermin-C3; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | 0.816 |
| Gsdmc2 | Gsdme | ENSMUSP00000140487 | ENSMUSP00000031845 | Gasdermin-C2; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | Gasdermin-E, C-terminal; Plays a role in the TP53-regulated cellular response to DNA damage probably by cooperating with TP53. | 0.834 |
| Gsdmc2 | Pjvk | ENSMUSP00000140487 | ENSMUSP00000097566 | Gasdermin-C2; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | Pejvakin; Essential in the activity of auditory pathway neurons; Belongs to the gasdermin family. | 0.705 |
| Gsdmc3 | Casp4 | ENSMUSP00000140272 | ENSMUSP00000027012 | Gasdermin-C3; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | Caspase-4 subunit p10; Proinflammatory caspase. Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non- canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS, as well as infection with Gram-negative bacteria. Independently of NLRP3 inflammasome and CASP1, promotes pyroptosis, through GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators. Plays a crucial role in the restriction of Salmonella typhimurium replication in colonic e [...] | 0.480 |
| Gsdmc3 | Gsdmc2 | ENSMUSP00000140272 | ENSMUSP00000140487 | Gasdermin-C3; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | Gasdermin-C2; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | 0.816 |
| Gsdmc3 | Gsdme | ENSMUSP00000140272 | ENSMUSP00000031845 | Gasdermin-C3; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | Gasdermin-E, C-terminal; Plays a role in the TP53-regulated cellular response to DNA damage probably by cooperating with TP53. | 0.840 |
| Gsdmc3 | Pjvk | ENSMUSP00000140272 | ENSMUSP00000097566 | Gasdermin-C3; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | Pejvakin; Essential in the activity of auditory pathway neurons; Belongs to the gasdermin family. | 0.736 |
| Gsdme | Casp4 | ENSMUSP00000031845 | ENSMUSP00000027012 | Gasdermin-E, C-terminal; Plays a role in the TP53-regulated cellular response to DNA damage probably by cooperating with TP53. | Caspase-4 subunit p10; Proinflammatory caspase. Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non- canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS, as well as infection with Gram-negative bacteria. Independently of NLRP3 inflammasome and CASP1, promotes pyroptosis, through GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators. Plays a crucial role in the restriction of Salmonella typhimurium replication in colonic e [...] | 0.763 |
| Gsdme | Gsdmc2 | ENSMUSP00000031845 | ENSMUSP00000140487 | Gasdermin-E, C-terminal; Plays a role in the TP53-regulated cellular response to DNA damage probably by cooperating with TP53. | Gasdermin-C2; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | 0.834 |
| Gsdme | Gsdmc3 | ENSMUSP00000031845 | ENSMUSP00000140272 | Gasdermin-E, C-terminal; Plays a role in the TP53-regulated cellular response to DNA damage probably by cooperating with TP53. | Gasdermin-C3; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | 0.840 |
| Pjvk | Casp4 | ENSMUSP00000097566 | ENSMUSP00000027012 | Pejvakin; Essential in the activity of auditory pathway neurons; Belongs to the gasdermin family. | Caspase-4 subunit p10; Proinflammatory caspase. Essential effector of NLRP3 inflammasome-dependent CASP1 activation and IL1B and IL18 secretion in response to non- canonical activators, such as UVB radiation, cholera enterotoxin subunit B and cytosolic LPS, as well as infection with Gram-negative bacteria. Independently of NLRP3 inflammasome and CASP1, promotes pyroptosis, through GSDMD cleavage and activation, and IL1A, IL18 and HMGB1 release in response to non-canonical inflammasome activators. Plays a crucial role in the restriction of Salmonella typhimurium replication in colonic e [...] | 0.617 |
| Pjvk | Gsdmc2 | ENSMUSP00000097566 | ENSMUSP00000140487 | Pejvakin; Essential in the activity of auditory pathway neurons; Belongs to the gasdermin family. | Gasdermin-C2; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | 0.705 |
| Pjvk | Gsdmc3 | ENSMUSP00000097566 | ENSMUSP00000140272 | Pejvakin; Essential in the activity of auditory pathway neurons; Belongs to the gasdermin family. | Gasdermin-C3; The N-terminal moiety promotes pyroptosis and exhibits bactericidal activity. The physiological relevance of these observations is unknown; Belongs to the gasdermin family. | 0.736 |