STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cysrt1Cysteine-rich tail protein 1; Belongs to the CYSRT1 family. (142 aa)    
Predicted Functional Partners:
Krt78
Keratin 78; Belongs to the intermediate filament family.
   
  
 0.764
Smim5
Small integral membrane protein 5.
   
  
 0.671
Kprp
Keratinocyte proline-rich protein.
   
   0.575
Ggt6
Glutathione hydrolase 6 heavy chain; Cleaves glutathione conjugates; Belongs to the gamma-glutamyltransferase family.
   
  
 0.570
Lypd3
Ly6/PLAUR domain-containing protein 3; Supports cell migration. May be involved in tumor progression (By similarity).
   
    0.567
Psapl1
Proactivator polypeptide-like 1; May activate the lysosomal degradation of sphingolipids.
   
    0.565
Lce3c
Late cornified envelope 3C.
   
   0.556
Trex2
Three prime repair exonuclease 2; Exonuclease with a preference for double-stranded DNA with mismatched 3' termini. May play a role in DNA repair.
   
    0.546
Lce1b
Late cornified envelope 1B.
   
    0.525
Calm4
Calmodulin-4; Implicated in the early stage of ectopic ossification.
   
    0.515
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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