node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arrb1 | Arrb2 | ENSMUSP00000095866 | ENSMUSP00000104208 | Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | Beta-arrestin-2; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | 0.959 |
Arrb1 | Olfr228 | ENSMUSP00000095866 | ENSMUSP00000149449 | Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | Olfactory receptor. | 0.672 |
Arrb2 | Arrb1 | ENSMUSP00000104208 | ENSMUSP00000095866 | Beta-arrestin-2; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | Beta-arrestin-1; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | 0.959 |
Arrb2 | Gnal | ENSMUSP00000104208 | ENSMUSP00000025402 | Beta-arrestin-2; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | Guanine nucleotide-binding protein G(olf) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters (By similarity); Belongs to the G-alpha family. G(s) subfamily. | 0.434 |
Arrb2 | Olfr228 | ENSMUSP00000104208 | ENSMUSP00000149449 | Beta-arrestin-2; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | Olfactory receptor. | 0.672 |
Bpifb9a | Gm4952 | ENSMUSP00000086314 | ENSMUSP00000090607 | Vomeromodulin. | Glycine N-acyltransferase-like protein; Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Can conjugate a multitude of substrates to form a variety of N-acylglycines (By similarity). | 0.552 |
Bpifb9a | Gm5155 | ENSMUSP00000086314 | ENSMUSP00000156991 | Vomeromodulin. | Predicted gene 5155. | 0.694 |
Bpifb9a | Olfr228 | ENSMUSP00000086314 | ENSMUSP00000149449 | Vomeromodulin. | Olfactory receptor. | 0.693 |
Bpifb9a | Spata21 | ENSMUSP00000086314 | ENSMUSP00000053080 | Vomeromodulin. | Spermatogenesis-associated protein 21; Involved in the differentiation of haploid spermatids. | 0.491 |
Gm4952 | Bpifb9a | ENSMUSP00000090607 | ENSMUSP00000086314 | Glycine N-acyltransferase-like protein; Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Can conjugate a multitude of substrates to form a variety of N-acylglycines (By similarity). | Vomeromodulin. | 0.552 |
Gm4952 | Gm5155 | ENSMUSP00000090607 | ENSMUSP00000156991 | Glycine N-acyltransferase-like protein; Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Can conjugate a multitude of substrates to form a variety of N-acylglycines (By similarity). | Predicted gene 5155. | 0.749 |
Gm4952 | Olfr228 | ENSMUSP00000090607 | ENSMUSP00000149449 | Glycine N-acyltransferase-like protein; Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Can conjugate a multitude of substrates to form a variety of N-acylglycines (By similarity). | Olfactory receptor. | 0.742 |
Gm4952 | Spata21 | ENSMUSP00000090607 | ENSMUSP00000053080 | Glycine N-acyltransferase-like protein; Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Can conjugate a multitude of substrates to form a variety of N-acylglycines (By similarity). | Spermatogenesis-associated protein 21; Involved in the differentiation of haploid spermatids. | 0.609 |
Gm5155 | Bpifb9a | ENSMUSP00000156991 | ENSMUSP00000086314 | Predicted gene 5155. | Vomeromodulin. | 0.694 |
Gm5155 | Gm4952 | ENSMUSP00000156991 | ENSMUSP00000090607 | Predicted gene 5155. | Glycine N-acyltransferase-like protein; Mitochondrial acyltransferase which transfers the acyl group to the N-terminus of glycine. Can conjugate a multitude of substrates to form a variety of N-acylglycines (By similarity). | 0.749 |
Gm5155 | Olfr228 | ENSMUSP00000156991 | ENSMUSP00000149449 | Predicted gene 5155. | Olfactory receptor. | 0.847 |
Gm5155 | Spata21 | ENSMUSP00000156991 | ENSMUSP00000053080 | Predicted gene 5155. | Spermatogenesis-associated protein 21; Involved in the differentiation of haploid spermatids. | 0.728 |
Gnal | Arrb2 | ENSMUSP00000025402 | ENSMUSP00000104208 | Guanine nucleotide-binding protein G(olf) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters (By similarity); Belongs to the G-alpha family. G(s) subfamily. | Beta-arrestin-2; Functions in regulating agonist-mediated G-protein coupled receptor (GPCR) signaling by mediating both receptor desensitization and resensitization processes. During homologous desensitization, beta- arrestins bind to the GPRK-phosphorylated receptor and sterically preclude its coupling to the cognate G-protein; the binding appears to require additional receptor determinants exposed only in the active receptor conformation. The beta-arrestins target many receptors for internalization by acting as endocytic adapters (CLASPs, clathrin- associated sorting proteins) and re [...] | 0.434 |
Gnal | Gnb1 | ENSMUSP00000025402 | ENSMUSP00000130123 | Guanine nucleotide-binding protein G(olf) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters (By similarity); Belongs to the G-alpha family. G(s) subfamily. | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction (By similarity). | 0.977 |
Gnal | Gng13 | ENSMUSP00000025402 | ENSMUSP00000131648 | Guanine nucleotide-binding protein G(olf) subunit alpha; Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. G(olf) alpha mediates signal transduction within the olfactory neuroepithelium and the basal ganglia. May be involved in some aspect of visual transduction, and in mediating the effect of one or more hormones/neurotransmitters (By similarity); Belongs to the G-alpha family. G(s) subfamily. | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-13; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. | 0.987 |