STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Prss34Mast cell protease-11; Belongs to the peptidase S1 family. (318 aa)    
Predicted Functional Partners:
Cpa3
Mast cell carboxypeptidase A.
   
 
 0.564
Cd200r3
Cell surface glycoprotein CD200 receptor 3; According to isoform 4 is a receptor for the CD200 cell surface glycoprotein. According to isoform 4 is not a receptor for the CD200/OX2 cell surface glycoprotein. Isoform 1, isoform 2 and isoform 3 are involved in the recruitment or surface expression of the TYROBP receptor. Isoform 6, isoform 7 and isoform 8 are not involved in the recruitment or surface expression of the TYROBP receptor; Belongs to the CD200R family.
   
 
 0.485
Cfap97d2
Uncharacterized protein CFAP97D2; Belongs to the CFAP97 family.
    
 
 0.466
Trmt9b
Probable tRNA methyltransferase 9B; May modifie wobble uridines in specific arginine and glutamic acid tRNAs. Acts as a tumor suppressor by promoting the expression of LIN9 (By similarity); Belongs to the methyltransferase superfamily.
    
 
 0.463
Zgrf1
Protein ZGRF1.
      
 0.458
Mrgpra4
Mas-related G-protein coupled receptor member A4; Orphan receptor. May be a receptor for RFamide-family neuropeptides such as NPFF and NPAF, which are analgesic in vivo. May regulate nociceptor function and/or development, including the sensation or modulation of pain.
      
 0.457
Triqk
Triple QxxK/R motif-containing protein; May play a role in cell growth and maintenance of cell morphology; Belongs to the TRIQK family.
      
 0.448
Purg
Purine-rich element-binding protein gamma.
      
 0.435
Fcer1a
High affinity immunoglobulin epsilon receptor subunit alpha; Binds to the Fc region of immunoglobulins epsilon. High affinity receptor. Responsible for initiating the allergic response. Binding of allergen to receptor-bound IgE leads to cell activation and the release of mediators (such as histamine) responsible for the manifestations of allergy. The same receptor also induces the secretion of important lymphokines.
   
 
 0.426
Lonrf1
LON peptidase N-terminal domain and RING finger protein 1.
    
 
 0.424
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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