STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ear6Eosinophil-associated, ribonuclease A family, member 6; Belongs to the pancreatic ribonuclease family. (155 aa)    
Predicted Functional Partners:
Ear1
Eosinophil cationic protein 1; Cytotoxin and helminthotoxin with ribonuclease activity. Possesses a wide variety of biological activities (By similarity). Belongs to the pancreatic ribonuclease family.
   
   
0.813
Rnase12
Probable inactive ribonuclease-like protein 12; Does not exhibit any ribonuclease activity; Belongs to the pancreatic ribonuclease family.
   
  
 0.639
Prg2
Eosinophil granule major basic protein; Cytotoxin and helminthotoxin. MBP also induces non-cytolytic histamine release from basophils. It is involved in antiparasitic defense mechanisms and immune hypersensitivity reactions (By similarity).
   
  
 0.578
Epx
Eosinophil peroxidase heavy chain; Mediates tyrosine nitration of secondary granule proteins in mature resting eosinophils; Belongs to the peroxidase family. XPO subfamily.
   
  
 0.553
Prg3
Proteoglycan 3; Possesses similar cytotoxic and cytostimulatory activities to PRG2/MBP.
   
  
 0.536
Cfap97d2
Uncharacterized protein CFAP97D2; Belongs to the CFAP97 family.
      
 0.518
Kbtbd12
Kelch repeat and BTB domain-containing protein 12.
      
 0.459
Nbdy
Negative regulator of P-body association.
      
 0.457
Triqk
Triple QxxK/R motif-containing protein; May play a role in cell growth and maintenance of cell morphology; Belongs to the TRIQK family.
      
 0.442
Rnh1
Ribonuclease inhibitor; Ribonuclease inhibitor which inhibits RNASE1, RNASE2 and ANG. May play a role in redox homeostasis (By similarity).
    
 
 0.425
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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