STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Shc2SHC-transforming protein 2. (573 aa)    
Predicted Functional Partners:
Grb2
Growth factor receptor-bound protein 2 isoform X1.
   
0.960
Met
Proto-oncogene tyrosine-protein kinase Met.
   
 0.959
Egfr
Epidermal growth factor receptor isoform X1.
    
 0.958
Erbb2
Receptor tyrosine-protein kinase erbB-2.
    
 0.958
Erbb4
Receptor tyrosine-protein kinase erbB-4 isoform X1.
    
 0.958
Erbb3
Receptor tyrosine-protein kinase erbB-3.
    
 0.958
Gab1
GRB2-associated-binding protein 1 isoform X1.
    
 0.957
Kdr
Vascular endothelial growth factor receptor 2.
   
 0.954
Igf1r
Insulin-like growth factor 1 receptor isoform X1.
    
 0.950
Insr
Insulin receptor isoform X1.
    
 0.950
Your Current Organism:
Mus pahari
NCBI taxonomy Id: 10093
Other names: Coelomys parahi, M. pahari, shrew mouse
Server load: low (18%) [HD]