STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Sirt1Sirtuin 1. (737 aa)    
Predicted Functional Partners:
Ppargc1a
Peroxisome proliferative activated receptor, gamma, coactivator 1 alpha.
    
 0.999
Trp53
Transformation related protein 53.
    
 0.997
Foxo3
Forkhead box O3.
    
 0.996
Foxo1
Forkhead box O1.
    
 0.996
Pparg
Peroxisome proliferator activated receptor gamma.
    
 0.994
Rela
V-rel reticuloendotheliosis viral oncogene homolog A (avian).
    
 0.992
Clock
Circadian locomotor output cycles kaput.
    
 0.991
Suv39h1
Suppressor of variegation 3-9 1.
    
 0.988
Nampt
Nicotinamide phosphoribosyltransferase.
     
 0.984
Ncor1
Nuclear receptor co-repressor 1.
   
 0.983
Your Current Organism:
Mus spretus
NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.