STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Erbb3Erb-b2 receptor tyrosine kinase 3. (1339 aa)    
Predicted Functional Partners:
Erbb2
Erb-b2 receptor tyrosine kinase 2.
  
 
0.999
Nrg2
Neuregulin 2.
    
 0.999
Egf
Epidermal growth factor.
   
 0.999
Nrg1
Neuregulin 1.
    
 0.999
Egfr
Epidermal growth factor receptor.
  
 
0.998
Shc1
Src homology 2 domain-containing transforming protein C1.
    
 0.998
Grb2
Growth factor receptor bound protein 2.
    
 0.995
Erbb4
Erb-b2 receptor tyrosine kinase 4.
  
 
0.993
Tgfa
Transforming growth factor alpha.
    
 0.993
Pik3r1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.992
Your Current Organism:
Mus spretus
NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.