STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LifLeukemia inhibitory factor. (203 aa)    
Predicted Functional Partners:
Lifr
LIF receptor alpha.
    
 0.999
Cntfr
Ciliary neurotrophic factor receptor.
     
 0.944
Il12rb2
Interleukin 12 receptor, beta 2.
    
 0.941
Il6st
Interleukin 6 signal transducer.
     
 0.933
Osmr
Oncostatin M receptor.
    
 0.922
Il27ra
Interleukin 27 receptor, alpha.
    
 0.913
Lepr
Leptin receptor.
     
 0.895
Ctf1
Cardiotrophin 1.
     
 0.879
Pdgfra
Platelet derived growth factor receptor, alpha polypeptide.
   
 
 0.865
Osm
Oncostatin M.
   
 
 0.852
Your Current Organism:
Mus spretus
NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.