STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tdp1tyrosyl-DNA phosphodiesterase 1. (609 aa)    
Predicted Functional Partners:
Top1
Topoisomerase (DNA) I.
    
 
 0.942
Top1mt
DNA topoisomerase 1, mitochondrial.
    
 
 0.886
Xrcc1
X-ray repair complementing defective repair in Chinese hamster cells 1.
   
 
 0.884
Polb
Polymerase (DNA directed), beta.
    
 
 0.878
Lig3
Ligase III, DNA, ATP-dependent.
   
 
 0.838
Pnkp
Polynucleotide kinase 3'- phosphatase.
    
 
 0.820
Ercc4
Excision repair cross-complementing rodent repair deficiency, complementation group 4.
   
 
 0.816
Xrcc6
X-ray repair complementing defective repair in Chinese hamster cells 6.
     
 0.801
Aptx
Aprataxin.
    
 
 0.789
Xrcc5
X-ray repair complementing defective repair in Chinese hamster cells 5.
    
 0.785
Your Current Organism:
Mus spretus
NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.