STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PtenPhosphatase and tensin homolog. (403 aa)    
Predicted Functional Partners:
Trp53
Transformation related protein 53.
   
 0.994
Pik3r1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.993
Dlg1
Discs large MAGUK scaffold protein 1.
   
 0.988
Ptk2
PTK2 protein tyrosine kinase 2.
    
 0.986
Pik3cd
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta.
    
 0.979
Pik3cb
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta.
    
 0.979
Pik3r2
Phosphoinositide-3-kinase regulatory subunit 2.
    
 0.978
Trim27
Tripartite motif-containing 27.
    
 0.975
Pik3ca
Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha.
   
 0.975
Csnk2a1
Casein kinase 2, alpha 1 polypeptide.
    
 0.972
Your Current Organism:
Mus spretus
NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.