STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Fgf8Fibroblast growth factor 8. (268 aa)    
Predicted Functional Partners:
Fgfr1
Fibroblast growth factor receptor 1.
    
 0.999
Fgfr2
Fibroblast growth factor receptor 2.
    
 0.997
Fgfr3
Fibroblast growth factor receptor 3.
    
 0.989
Fgfr4
Fibroblast growth factor receptor 4.
    
 0.984
Fgfrl1
Fibroblast growth factor receptor-like 1.
    
 0.936
Kdr
Kinase insert domain protein receptor.
    
 0.925
Kl
Klotho.
    
 0.920
Flt4
FMS-like tyrosine kinase 4.
    
 0.909
Pdgfra
Platelet derived growth factor receptor, alpha polypeptide.
    
 0.888
Pdgfrb
Platelet derived growth factor receptor, beta polypeptide.
    
 0.869
Your Current Organism:
Mus spretus
NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.