STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SufuSUFU negative regulator of hedgehog signaling. (485 aa)    
Predicted Functional Partners:
Gli2
GLI-Kruppel family member GLI2.
    
 0.999
Gli1
GLI-Kruppel family member GLI1.
    
 0.999
Gli3
GLI-Kruppel family member GLI3.
    
 0.999
Kif7
Kinesin family member 7.
    
 0.999
Stk36
Serine/threonine kinase 36.
    
 0.990
Smo
Smoothened, frizzled class receptor.
     
 0.990
Ulk3
Unc-51-like kinase 3.
     
 0.984
Gsk3b
Glycogen synthase kinase 3 beta.
    
 0.963
Cul3
Cullin 3.
     
 0.957
Ulk4
Unc-51-like kinase 4.
    
 0.950
Your Current Organism:
Mus spretus
NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.