STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SirpaSignal-regulatory protein alpha. (513 aa)    
Predicted Functional Partners:
Cd47
CD47 antigen (Rh-related antigen, integrin-associated signal transducer).
   
 0.999
Ptpn11
Protein tyrosine phosphatase, non-receptor type 11.
    
 0.999
Ptpn6
Protein tyrosine phosphatase, non-receptor type 6.
    
 0.973
Trem2
Triggering receptor expressed on myeloid cells 2.
   
 0.953
Tyrobp
TYRO protein tyrosine kinase binding protein.
   
 0.908
Syk
Spleen tyrosine kinase.
   
 0.865
Src
Rous sarcoma oncogene.
   
 0.850
MGP_SPRETEiJ_P0059218
annotation not available
  
  
 
0.814
MGP_SPRETEiJ_P0059219
annotation not available
  
  
 
0.814
Fcgr2b
Fc receptor, IgG, low affinity IIb.
   
 0.807
Your Current Organism:
Mus spretus
NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.