STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ptch2Patched 2. (1182 aa)    
Predicted Functional Partners:
Shh
Sonic hedgehog.
   
 0.999
Ihh
Indian hedgehog.
    
 0.998
Dhh
Desert hedgehog.
    
 0.998
Smo
Smoothened, frizzled class receptor.
    
 0.994
Boc
Biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein.
    
 0.950
Cdon
Cell adhesion molecule-related/down-regulated by oncogenes.
    
 0.947
Gas1
Growth arrest specific 1.
     
 0.917
Smurf2
SMAD specific E3 ubiquitin protein ligase 2.
    
 0.893
Ptch1
Patched 1.
  
  
0.877
Smurf1
SMAD specific E3 ubiquitin protein ligase 1.
    
 0.875
Your Current Organism:
Mus spretus
NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.