STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Yes1YES proto-oncogene 1, Src family tyrosine kinase. (620 aa)    
Predicted Functional Partners:
Fyn
Fyn proto-oncogene.
  
0.978
Shc1
Src homology 2 domain-containing transforming protein C1.
   
0.963
Ptpn11
Protein tyrosine phosphatase, non-receptor type 11.
   
0.960
Egfr
Epidermal growth factor receptor.
    
0.925
Plcg2
Phospholipase C, gamma 2.
    
0.925
Inppl1
Inositol polyphosphate phosphatase-like 1.
   
 0.923
Ptk2
PTK2 protein tyrosine kinase 2.
   
0.919
Grap2
GRB2-related adaptor protein 2.
    
0.918
Src
Rous sarcoma oncogene.
  
  
 
0.918
Csk
C-src tyrosine kinase.
  
0.900
Your Current Organism:
Mus spretus
NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.