STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Dcun1d2DCN1, defective in cullin neddylation 1, domain containing 2 (S. cerevisiae). (259 aa)    
Predicted Functional Partners:
Cul1
Cullin 1.
   
 0.946
Ube2m
Ubiquitin-conjugating enzyme E2M.
    
 0.936
Cul3
Cullin 3.
   
 0.934
Rbx1
Ring-box 1.
    
 0.932
Nedd8
Neural precursor cell expressed, developmentally down-regulated gene 8.
    
 0.901
Cul5
Cullin 5.
   
 0.853
Ube2f
Ubiquitin-conjugating enzyme E2F (putative).
    
 0.847
MGP_SPRETEiJ_P0033634
annotation not available
    
 0.847
Cul2
Cullin 2.
   
 0.830
Cul4a
Cullin 4A.
    
 0.802
Your Current Organism:
Mus spretus
NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.