STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Foxl1Forkhead box L1. (336 aa)    
Predicted Functional Partners:
Tcf7l2
Transcription factor 7 like 2, T cell specific, HMG box.
    
 
 0.574
Ctnnb1
Catenin (cadherin associated protein), beta 1.
    
 0.562
Sirt1
Sirtuin 1.
    
 0.533
Mthfsd
Methenyltetrahydrofolate synthetase domain containing.
      
 0.520
Lgr5
Leucine rich repeat containing G protein coupled receptor 5.
      
 0.516
Nkx2-3
NK2 homeobox 3.
    
 
 0.512
Suox
Sulfite oxidase.
     
 0.498
Npm3
Nucleoplasmin 3.
    
 
 0.493
Pitx1
Paired-like homeodomain transcription factor 1.
    
 
 0.475
Sgk3
Serum/glucocorticoid regulated kinase 3.
    
 0.466
Your Current Organism:
Mus spretus
NCBI taxonomy Id: 10096
Other names: Algerian mouse, M. spretus, Mus musculus spretus, western wild mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.