node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AcoD | AcsA | SAMN05192578_11340 | SAMN05192578_1079 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.938 |
AcoD | MaeB | SAMN05192578_11340 | SAMN05192578_10794 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Allosteric NADP-dependent malic enzyme. | 0.486 |
AcoD | PoxB | SAMN05192578_11340 | SAMN05192578_1011257 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family. | 0.910 |
AcsA | AcoD | SAMN05192578_1079 | SAMN05192578_11340 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. | 0.938 |
AcsA | BfmBAB | SAMN05192578_1079 | SAMN05192578_105130 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.839 |
AcsA | CalB_1 | SAMN05192578_1079 | SAMN05192578_105217 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. | 0.938 |
AcsA | CalB_2 | SAMN05192578_1079 | SAMN05192578_105282 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. | 0.938 |
AcsA | MaeB | SAMN05192578_1079 | SAMN05192578_10794 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Allosteric NADP-dependent malic enzyme. | 0.582 |
AcsA | PoxB | SAMN05192578_1079 | SAMN05192578_1011257 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family. | 0.914 |
AcsA | pdhA | SAMN05192578_1079 | SAMN05192578_106163 | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.836 |
BfmBAB | AcsA | SAMN05192578_105130 | SAMN05192578_1079 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.839 |
BfmBAB | IlvH | SAMN05192578_105130 | SAMN05192578_10640 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Acetolactate synthase, small subunit. | 0.836 |
BfmBAB | LldD | SAMN05192578_105130 | SAMN05192578_106178 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | L-lactate dehydrogenase (cytochrome). | 0.900 |
BfmBAB | MaeB | SAMN05192578_105130 | SAMN05192578_10794 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Allosteric NADP-dependent malic enzyme. | 0.962 |
BfmBAB | PoxB | SAMN05192578_105130 | SAMN05192578_1011257 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Pyruvate dehydrogenase (quinone); Belongs to the TPP enzyme family. | 0.912 |
BfmBAB | Pyk | SAMN05192578_105130 | SAMN05192578_106169 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Pyruvate kinase; Belongs to the pyruvate kinase family. | 0.918 |
BfmBAB | pdhA | SAMN05192578_105130 | SAMN05192578_106163 | Pyruvate dehydrogenase E1 component beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | Pyruvate dehydrogenase E1 component alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
CalB_1 | AcsA | SAMN05192578_105217 | SAMN05192578_1079 | Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. | Acetyl-coenzyme A synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA. | 0.938 |
CalB_1 | CalB_2 | SAMN05192578_105217 | SAMN05192578_105282 | Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. | Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. | 0.909 |
CalB_1 | MaeB | SAMN05192578_105217 | SAMN05192578_10794 | Aldehyde dehydrogenase (NAD+); Belongs to the aldehyde dehydrogenase family. | Allosteric NADP-dependent malic enzyme. | 0.486 |