Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Sirt7Sirtuin 7. (402 aa)    
Predicted Functional Partners:
ENSMSIP00000018561
annotation not available
    
 0.950
Ddb1
Damage specific DNA binding protein 1.
    
 
 0.946
Sirt5
Sirtuin 5.
    
 0.942
ENSMSIP00000012770
annotation not available
     
 0.929
Sarm1
Sterile alpha and HEAT/Armadillo motif containing 1.
     
 0.927
Cd38
CD38 antigen.
     
 0.923
Polr1a
Polymerase (RNA) I polypeptide A.
    
 
 0.918
Wdr77
WD repeat domain 77.
    
  0.916
ENSMSIP00000016968
annotation not available
     
 0.912
Sirt2
Sirtuin 2.
     
 0.902
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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