STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Shc2SHC (Src homology 2 domain containing) transforming protein 2. (573 aa)    
Predicted Functional Partners:
Erbb3
Erb-b2 receptor tyrosine kinase 3.
    
 0.985
Egfr
Epidermal growth factor receptor.
    
 0.985
Erbb4
Erb-b2 receptor tyrosine kinase 4.
    
 0.985
Erbb2
Erb-b2 receptor tyrosine kinase 2.
    
 0.985
Igf1r
Insulin-like growth factor I receptor.
    
 0.961
Insr
Insulin receptor.
    
 0.961
Ntrk2
Neurotrophic tyrosine kinase, receptor, type 2.
    
 0.958
Kdr
Kinase insert domain protein receptor.
    
 0.957
Kit
KIT proto-oncogene receptor tyrosine kinase.
    
 0.955
Ntrk1
Neurotrophic tyrosine kinase, receptor, type 1.
    
 0.955
Your Current Organism:
Mus spicilegus
NCBI taxonomy Id: 10103
Other names: M. spicilegus, Mus hortulanus, mound-building mouse, steppe mouse
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.